Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture
High-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers. From 3D anaglyphs, trabecular rod thickness and length were measured and the trabec...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Journal of Osteoporosis |
| Online Access: | http://dx.doi.org/10.4061/2010/641578 |
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| author | Ian H. Parkinson Danielle Forbes Peter Sutton-Smith Nicola L. Fazzalari |
| author_facet | Ian H. Parkinson Danielle Forbes Peter Sutton-Smith Nicola L. Fazzalari |
| author_sort | Ian H. Parkinson |
| collection | DOAJ |
| description | High-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers. From 3D anaglyphs, trabecular rod thickness and length were measured and the trabecular rod Buckling index was calculated. From 3D voxel-based datasets, bone volume density, trabecular thickness, and trabecular separation were measured. Also, trabecular bone pattern factor, structural model index, connectivity density, and degree of anisotropy were calculated. Bone volume density alone explains 59% of the variability in trabecular rod Buckling index. The addition of connectivity density, trabecular separation, and structural model index, in a multiple regression statistical model, improves the explanatory power to 77%. The relationships between measures of cancellous bone architecture and a derived measure of trabecular rod strength were investigated. Morphological descriptors of cancellous bone provide a composite explanatory model of trabecular rod strength. |
| format | Article |
| id | doaj-art-b68bf8f9478c4dd3ba08c4b48eb89203 |
| institution | Kabale University |
| issn | 2042-0064 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Osteoporosis |
| spelling | doaj-art-b68bf8f9478c4dd3ba08c4b48eb892032025-02-03T01:09:09ZengWileyJournal of Osteoporosis2042-00642010-01-01201010.4061/2010/641578641578Model-Independent 3D Descriptors of Vertebral Cancellous Bone ArchitectureIan H. Parkinson0Danielle Forbes1Peter Sutton-Smith2Nicola L. Fazzalari3Bone and Joint Research Laboratory, SA Pathology and Hanson Institute, Discipline of Pathology, University of Adelaide, Adelaide, South Australia 5000, AustraliaBone and Joint Research Laboratory, SA Pathology and Hanson Institute, Discipline of Pathology, University of Adelaide, Adelaide, South Australia 5000, AustraliaBone and Joint Research Laboratory, SA Pathology and Hanson Institute, Discipline of Pathology, University of Adelaide, Adelaide, South Australia 5000, AustraliaBone and Joint Research Laboratory, SA Pathology and Hanson Institute, Discipline of Pathology, University of Adelaide, Adelaide, South Australia 5000, AustraliaHigh-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers. From 3D anaglyphs, trabecular rod thickness and length were measured and the trabecular rod Buckling index was calculated. From 3D voxel-based datasets, bone volume density, trabecular thickness, and trabecular separation were measured. Also, trabecular bone pattern factor, structural model index, connectivity density, and degree of anisotropy were calculated. Bone volume density alone explains 59% of the variability in trabecular rod Buckling index. The addition of connectivity density, trabecular separation, and structural model index, in a multiple regression statistical model, improves the explanatory power to 77%. The relationships between measures of cancellous bone architecture and a derived measure of trabecular rod strength were investigated. Morphological descriptors of cancellous bone provide a composite explanatory model of trabecular rod strength.http://dx.doi.org/10.4061/2010/641578 |
| spellingShingle | Ian H. Parkinson Danielle Forbes Peter Sutton-Smith Nicola L. Fazzalari Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture Journal of Osteoporosis |
| title | Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture |
| title_full | Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture |
| title_fullStr | Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture |
| title_full_unstemmed | Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture |
| title_short | Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture |
| title_sort | model independent 3d descriptors of vertebral cancellous bone architecture |
| url | http://dx.doi.org/10.4061/2010/641578 |
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