The Fetal Origins of the Metabolic Syndrome: Can We Intervene?
Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases ar...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2012/482690 |
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| _version_ | 1832552038985105408 |
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| author | Noelle Ma Daniel B. Hardy |
| author_facet | Noelle Ma Daniel B. Hardy |
| author_sort | Noelle Ma |
| collection | DOAJ |
| description | Epidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies. |
| format | Article |
| id | doaj-art-b6632ecbcbd542e3aa211e3239a21ce0 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-b6632ecbcbd542e3aa211e3239a21ce02025-02-03T05:59:44ZengWileyJournal of Pregnancy2090-27272090-27352012-01-01201210.1155/2012/482690482690The Fetal Origins of the Metabolic Syndrome: Can We Intervene?Noelle Ma0Daniel B. Hardy1The Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, N6A 5C1, CanadaThe Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, N6A 5C1, CanadaEpidemiological studies have suggested that metabolic programming begins during fetal life and adverse events in utero are a critical factor in the etiology of chronic diseases and overall health. While the underlying molecular mechanisms linking impaired fetal development to these adult diseases are being elucidated, little is known about how we can intervene early in life to diminish the incidence and severity of these long-term diseases. This paper highlights the latest clinical and pharmaceutical studies addressing how dietary intervention in fetal and neonatal life may be able to prevent aspects of the metabolic syndrome associated with IUGR pregnancies.http://dx.doi.org/10.1155/2012/482690 |
| spellingShingle | Noelle Ma Daniel B. Hardy The Fetal Origins of the Metabolic Syndrome: Can We Intervene? Journal of Pregnancy |
| title | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
| title_full | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
| title_fullStr | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
| title_full_unstemmed | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
| title_short | The Fetal Origins of the Metabolic Syndrome: Can We Intervene? |
| title_sort | fetal origins of the metabolic syndrome can we intervene |
| url | http://dx.doi.org/10.1155/2012/482690 |
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