Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.

<h4>Background</h4>Altered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition resulting from Pol beta over-expression has not yet been evaluated in a mouse model.<h4>Methodology/princip...

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Bibliographic Details
Main Authors: Katsuhiko Yoshizawa, Elena Jelezcova, Ashley R Brown, Julie F Foley, Abraham Nyska, Xiangli Cui, Lorne J Hofseth, Robert M Maronpot, Samuel H Wilson, Antonia R Sepulveda, Robert W Sobol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006493&type=printable
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