Pregnancy and the Biliary System
Alterations in the synthesis and secretion of bile salts and cholesterol and in gallbladder function occur during pregnancy. These changes are related to the effects of estrogen and progesterone. Biliary cholesterol saturation and the cholic acid/chenodeoxycholic acid ratio increase. Progesterone al...
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Format: | Article |
Language: | English |
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Wiley
1990-01-01
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Series: | Canadian Journal of Gastroenterology |
Online Access: | http://dx.doi.org/10.1155/1990/582650 |
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author | Helga Witt J Joseph Connon |
author_facet | Helga Witt J Joseph Connon |
author_sort | Helga Witt |
collection | DOAJ |
description | Alterations in the synthesis and secretion of bile salts and
cholesterol and in gallbladder function occur during pregnancy. These changes
are related to the effects of estrogen and progesterone. Biliary cholesterol saturation
and the cholic acid/chenodeoxycholic acid ratio increase. Progesterone also
diminishes gallbladder contractility and emptying. Gallstones occur in 2.5 to
11% of pregnant women and are associated with cholecystitis in 0.008 to 0.1%
of pregnant women. Operative treatment should be deferred if possible until after
delivery; failing that, surgery is best done in the second trimester. Endoscopic
pap1llotomy may prove to be the best therapy for choledocholithiasis. |
format | Article |
id | doaj-art-b648bb1dfa5b4a55b9748e19dd91f4c1 |
institution | Kabale University |
issn | 0835-7900 |
language | English |
publishDate | 1990-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Gastroenterology |
spelling | doaj-art-b648bb1dfa5b4a55b9748e19dd91f4c12025-02-03T01:24:27ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-014520921410.1155/1990/582650Pregnancy and the Biliary SystemHelga WittJ Joseph ConnonAlterations in the synthesis and secretion of bile salts and cholesterol and in gallbladder function occur during pregnancy. These changes are related to the effects of estrogen and progesterone. Biliary cholesterol saturation and the cholic acid/chenodeoxycholic acid ratio increase. Progesterone also diminishes gallbladder contractility and emptying. Gallstones occur in 2.5 to 11% of pregnant women and are associated with cholecystitis in 0.008 to 0.1% of pregnant women. Operative treatment should be deferred if possible until after delivery; failing that, surgery is best done in the second trimester. Endoscopic pap1llotomy may prove to be the best therapy for choledocholithiasis.http://dx.doi.org/10.1155/1990/582650 |
spellingShingle | Helga Witt J Joseph Connon Pregnancy and the Biliary System Canadian Journal of Gastroenterology |
title | Pregnancy and the Biliary System |
title_full | Pregnancy and the Biliary System |
title_fullStr | Pregnancy and the Biliary System |
title_full_unstemmed | Pregnancy and the Biliary System |
title_short | Pregnancy and the Biliary System |
title_sort | pregnancy and the biliary system |
url | http://dx.doi.org/10.1155/1990/582650 |
work_keys_str_mv | AT helgawitt pregnancyandthebiliarysystem AT jjosephconnon pregnancyandthebiliarysystem |