Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer.

Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer.

<h4>Background</h4>Highly sensitive and specific urine-based tests to detect either primary or recurrent bladder cancer have proved elusive to date. Our ever increasing knowledge of the genomic aberrations in bladder cancer should enable the development of such tests based on urinary DNA...

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Main Authors: Douglas G Ward, Laura Baxter, Naheema S Gordon, Sascha Ott, Richard S Savage, Andrew D Beggs, Jonathan D James, Jennifer Lickiss, Shaun Green, Yvonne Wallis, Wenbin Wei, Nicholas D James, Maurice P Zeegers, K K Cheng, Glenn M Mathews, Prashant Patel, Michael Griffiths, Richard T Bryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0149756
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