Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo
Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue. Obesity is associated with elevated hepcidin concentrations and iron depletion sug...
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Main Authors: | Lisa Tussing-Humphreys, Keith N. Frayn, Steven R. Smith, Mark Westerman, A. Louise Dennis, Elizabeta Nemeth, Jessica Thomson, Cenk Pusatcioglu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1100/2011/634861 |
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