Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus
Patients with systemic lupus erythematosus (SLE) are at increased risk for infection including opportunistic infections. Fungal infection in particular can be difficult to diagnose and treat and often can be life-threatening in the immunocompromised patient. We present a case in which a patient with...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2020/9623198 |
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| author | Rochelle Hardie Tracian James-Goulbourne Monsoon Rashid Jeremy Sullivan Yamen Homsi |
| author_facet | Rochelle Hardie Tracian James-Goulbourne Monsoon Rashid Jeremy Sullivan Yamen Homsi |
| author_sort | Rochelle Hardie |
| collection | DOAJ |
| description | Patients with systemic lupus erythematosus (SLE) are at increased risk for infection including opportunistic infections. Fungal infection in particular can be difficult to diagnose and treat and often can be life-threatening in the immunocompromised patient. We present a case in which a patient with SLE presented to the hospital with shortness of breath and cough. Throughout the hospital course, the patient’s condition continued to decline leading to acute respiratory failure, and eventually, the patient expired. Postmortem autopsy revealed invasive fungal aspergillosis infection involving the heart, lungs, and brain. Earlier diagnosis and treatment with empiric antifungals may improve survival in these patients. |
| format | Article |
| id | doaj-art-b6138a17444d4900a03e0d11d2f8a33b |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-b6138a17444d4900a03e0d11d2f8a33b2025-02-03T06:43:39ZengWileyCase Reports in Infectious Diseases2090-66252090-66332020-01-01202010.1155/2020/96231989623198Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus ErythematosusRochelle Hardie0Tracian James-Goulbourne1Monsoon Rashid2Jeremy Sullivan3Yamen Homsi4Division of Infection Disease, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USADivision of Internal Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USADivision of Internal Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USADivision of Internal Medicine, NYU Langone Hospital-Brooklyn, 150 55th St, Brooklyn, NY 11220, USADivision of Rheumatology, NYU Langone Hospital-Brooklyn, 150 55th St, Brooklyn, NY 11220, USAPatients with systemic lupus erythematosus (SLE) are at increased risk for infection including opportunistic infections. Fungal infection in particular can be difficult to diagnose and treat and often can be life-threatening in the immunocompromised patient. We present a case in which a patient with SLE presented to the hospital with shortness of breath and cough. Throughout the hospital course, the patient’s condition continued to decline leading to acute respiratory failure, and eventually, the patient expired. Postmortem autopsy revealed invasive fungal aspergillosis infection involving the heart, lungs, and brain. Earlier diagnosis and treatment with empiric antifungals may improve survival in these patients.http://dx.doi.org/10.1155/2020/9623198 |
| spellingShingle | Rochelle Hardie Tracian James-Goulbourne Monsoon Rashid Jeremy Sullivan Yamen Homsi Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus Case Reports in Infectious Diseases |
| title | Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus |
| title_full | Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus |
| title_fullStr | Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus |
| title_full_unstemmed | Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus |
| title_short | Fatal Disseminated Aspergillosis in a Patient with Systemic Lupus Erythematosus |
| title_sort | fatal disseminated aspergillosis in a patient with systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2020/9623198 |
| work_keys_str_mv | AT rochellehardie fataldisseminatedaspergillosisinapatientwithsystemiclupuserythematosus AT tracianjamesgoulbourne fataldisseminatedaspergillosisinapatientwithsystemiclupuserythematosus AT monsoonrashid fataldisseminatedaspergillosisinapatientwithsystemiclupuserythematosus AT jeremysullivan fataldisseminatedaspergillosisinapatientwithsystemiclupuserythematosus AT yamenhomsi fataldisseminatedaspergillosisinapatientwithsystemiclupuserythematosus |