Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review

Pulmonary embolism (PE) remains a critical condition with significant mortality and morbidity, necessitating timely detection and intervention to improve patient outcomes. This review examines the evolving role of artificial intelligence (AI) in PE management. Two primary AI-driven models that are c...

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Main Authors: Ahmad Moayad Naser, Rhea Vyas, Ahmed Ashraf Morgan, Abdul Mukhtadir Kalaiger, Amrin Kharawala, Sanjana Nagraj, Raksheeth Agarwal, Maisha Maliha, Shaunak Mangeshkar, Nikita Singh, Vikyath Satish, Sheetal Mathai, Leonidas Palaiodimos, Robert T. Faillace
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/7/889
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author Ahmad Moayad Naser
Rhea Vyas
Ahmed Ashraf Morgan
Abdul Mukhtadir Kalaiger
Amrin Kharawala
Sanjana Nagraj
Raksheeth Agarwal
Maisha Maliha
Shaunak Mangeshkar
Nikita Singh
Vikyath Satish
Sheetal Mathai
Leonidas Palaiodimos
Robert T. Faillace
author_facet Ahmad Moayad Naser
Rhea Vyas
Ahmed Ashraf Morgan
Abdul Mukhtadir Kalaiger
Amrin Kharawala
Sanjana Nagraj
Raksheeth Agarwal
Maisha Maliha
Shaunak Mangeshkar
Nikita Singh
Vikyath Satish
Sheetal Mathai
Leonidas Palaiodimos
Robert T. Faillace
author_sort Ahmad Moayad Naser
collection DOAJ
description Pulmonary embolism (PE) remains a critical condition with significant mortality and morbidity, necessitating timely detection and intervention to improve patient outcomes. This review examines the evolving role of artificial intelligence (AI) in PE management. Two primary AI-driven models that are currently being explored are deep convolutional neural networks (DCNNs) for enhanced image-based detection and natural language processing (NLP) for improved risk stratification using electronic health records. A major advancement in this field was the FDA approval of the Aidoc© AI model, which has demonstrated high specificity and negative predictive value in PE diagnosis from imaging scans. Additionally, AI is being explored for optimizing anticoagulation strategies and predicting PE recurrence risk. While further large-scale studies are needed to fully establish AI’s role in clinical practice, its integration holds significant potential to enhance diagnostic accuracy and overall patient management.
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issn 2075-4418
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publishDate 2025-04-01
publisher MDPI AG
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series Diagnostics
spelling doaj-art-b5fcab0f619c4fea81d6e56f0ff20f302025-08-20T03:06:29ZengMDPI AGDiagnostics2075-44182025-04-0115788910.3390/diagnostics15070889Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive ReviewAhmad Moayad Naser0Rhea Vyas1Ahmed Ashraf Morgan2Abdul Mukhtadir Kalaiger3Amrin Kharawala4Sanjana Nagraj5Raksheeth Agarwal6Maisha Maliha7Shaunak Mangeshkar8Nikita Singh9Vikyath Satish10Sheetal Mathai11Leonidas Palaiodimos12Robert T. Faillace13Department of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, Montefiore Wakefield Medical Center, New York, NY 10461, USADepartment of Cardiology, University of Nebraska Medical Center, Omaha, NE 68198, USADepartment of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USADepartment of Medicine, New York City Health + Hospitals/Jacobi, Albert Einstein College of Medicine, New York, NY 10461, USAPulmonary embolism (PE) remains a critical condition with significant mortality and morbidity, necessitating timely detection and intervention to improve patient outcomes. This review examines the evolving role of artificial intelligence (AI) in PE management. Two primary AI-driven models that are currently being explored are deep convolutional neural networks (DCNNs) for enhanced image-based detection and natural language processing (NLP) for improved risk stratification using electronic health records. A major advancement in this field was the FDA approval of the Aidoc© AI model, which has demonstrated high specificity and negative predictive value in PE diagnosis from imaging scans. Additionally, AI is being explored for optimizing anticoagulation strategies and predicting PE recurrence risk. While further large-scale studies are needed to fully establish AI’s role in clinical practice, its integration holds significant potential to enhance diagnostic accuracy and overall patient management.https://www.mdpi.com/2075-4418/15/7/889artificial intelligenceartificial neural networksdeep convolutional neural networks (DCNN)machine learningnatural language processing (NLP)pulmonary embolism
spellingShingle Ahmad Moayad Naser
Rhea Vyas
Ahmed Ashraf Morgan
Abdul Mukhtadir Kalaiger
Amrin Kharawala
Sanjana Nagraj
Raksheeth Agarwal
Maisha Maliha
Shaunak Mangeshkar
Nikita Singh
Vikyath Satish
Sheetal Mathai
Leonidas Palaiodimos
Robert T. Faillace
Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
Diagnostics
artificial intelligence
artificial neural networks
deep convolutional neural networks (DCNN)
machine learning
natural language processing (NLP)
pulmonary embolism
title Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
title_full Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
title_fullStr Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
title_full_unstemmed Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
title_short Role of Artificial Intelligence in the Diagnosis and Management of Pulmonary Embolism: A Comprehensive Review
title_sort role of artificial intelligence in the diagnosis and management of pulmonary embolism a comprehensive review
topic artificial intelligence
artificial neural networks
deep convolutional neural networks (DCNN)
machine learning
natural language processing (NLP)
pulmonary embolism
url https://www.mdpi.com/2075-4418/15/7/889
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