Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report

Introduction. Late-onset bleb leaks occur more frequently after the use of adjunctive antimetabolites and require surgical management to seal and preserve filtrating bleb. Case Presentation. A 48-year-old female presented with decreased visual acuity for five days in her left eye. She had a left pen...

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Main Authors: Zuleyha Yalniz-Akkaya, Ayse Burcu, Firdevs Ornek
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2012/810751
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author Zuleyha Yalniz-Akkaya
Ayse Burcu
Firdevs Ornek
author_facet Zuleyha Yalniz-Akkaya
Ayse Burcu
Firdevs Ornek
author_sort Zuleyha Yalniz-Akkaya
collection DOAJ
description Introduction. Late-onset bleb leaks occur more frequently after the use of adjunctive antimetabolites and require surgical management to seal and preserve filtrating bleb. Case Presentation. A 48-year-old female presented with decreased visual acuity for five days in her left eye. She had a left penetrating keratoplasty one year earlier and two trabeculectomies 7 years earlier. Visual acuity was hand motions, intraocular pressure was 3 mmHg, corneal graft was clear, mature cataract was present, and axial length was 30.48 mm. The conjunctiva covering the superotemporal sclerotomy was avascular, flat, and partially lost. After heavily painting the bleb with a fluorescein, late-onset point leak was revealed. Overlying conjunctiva was excised. The atrophic, irregular, and partially absent scleral flap was covered by a processed human pericardium graft and conjunctival advancement. Postoperatively, intraocular pressure stabilized around 16 mmHg. After four months, phacoemulsification and intraocular lens implantation were performed. Visual acuity did not exceed 0.1 (in decimal notation) due to degenerative myopia-related macular atrophy. Corneal graft remained clear at her 6-month followup period. Conclusion. Surgical bleb revision using a pericardium graft and conjunctival advancement seems to be an effective method for treating late bleb leaks. However, careful follow-up is required for detecting recurrent leaks and elevated intraocular pressure.
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spelling doaj-art-b5f2f5390dfe490d988f34a98fa0c35d2025-02-03T01:02:09ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302012-01-01201210.1155/2012/810751810751Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case ReportZuleyha Yalniz-Akkaya0Ayse Burcu1Firdevs Ornek2Ophthalmolgy Clinic, Ministry of Health Ankara Training and Research Hospital, TR06340 Ankara, TurkeyOphthalmolgy Clinic, Ministry of Health Ankara Training and Research Hospital, TR06340 Ankara, TurkeyOphthalmolgy Clinic, Ministry of Health Ankara Training and Research Hospital, TR06340 Ankara, TurkeyIntroduction. Late-onset bleb leaks occur more frequently after the use of adjunctive antimetabolites and require surgical management to seal and preserve filtrating bleb. Case Presentation. A 48-year-old female presented with decreased visual acuity for five days in her left eye. She had a left penetrating keratoplasty one year earlier and two trabeculectomies 7 years earlier. Visual acuity was hand motions, intraocular pressure was 3 mmHg, corneal graft was clear, mature cataract was present, and axial length was 30.48 mm. The conjunctiva covering the superotemporal sclerotomy was avascular, flat, and partially lost. After heavily painting the bleb with a fluorescein, late-onset point leak was revealed. Overlying conjunctiva was excised. The atrophic, irregular, and partially absent scleral flap was covered by a processed human pericardium graft and conjunctival advancement. Postoperatively, intraocular pressure stabilized around 16 mmHg. After four months, phacoemulsification and intraocular lens implantation were performed. Visual acuity did not exceed 0.1 (in decimal notation) due to degenerative myopia-related macular atrophy. Corneal graft remained clear at her 6-month followup period. Conclusion. Surgical bleb revision using a pericardium graft and conjunctival advancement seems to be an effective method for treating late bleb leaks. However, careful follow-up is required for detecting recurrent leaks and elevated intraocular pressure.http://dx.doi.org/10.1155/2012/810751
spellingShingle Zuleyha Yalniz-Akkaya
Ayse Burcu
Firdevs Ornek
Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
Case Reports in Ophthalmological Medicine
title Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
title_full Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
title_fullStr Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
title_full_unstemmed Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
title_short Late-Onset Glaucoma-Filtrating Bleb Leak in a Penetrating Keratoplasty Patient: A Case Report
title_sort late onset glaucoma filtrating bleb leak in a penetrating keratoplasty patient a case report
url http://dx.doi.org/10.1155/2012/810751
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AT ayseburcu lateonsetglaucomafiltratingblebleakinapenetratingkeratoplastypatientacasereport
AT firdevsornek lateonsetglaucomafiltratingblebleakinapenetratingkeratoplastypatientacasereport