Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6

Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6

Mitogen inducible gene-6 (Mig-6) is a feedback inhibitor of epidermal growth factor receptor (EGFR) signaling pathway. The liver-specific knockout mice of the Mig-6 gene (Mig-6d/d) showed hepatomegaly and increased hypercholesterolemia. In this study, the biomarkers of insulin resistance and the eff...

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Bibliographic Details
Main Authors:	Byung Kil Park, Eun-Ah Lee, Hee-Youn Kim, Jun Choul Lee, Koon Soon Kim, Won Hoon Jeong, Ki Young Kim, Bon Jeong Ku, Sang Dal Rhee
Format:	Article
Language:	English
Published:	Wiley 2016-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2016/1632061
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