A metal-trap tests and refines blueprints to engineer cellular protein metalation with different elements
Abstract It has been challenging to test how proteins acquire specific metals in cells. The speciation of metalation is thought to depend on the preferences of proteins for different metals competing at intracellular metal-availabilities. This implies mis-metalation may occur if proteins become mis-...
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Main Authors: | Sophie E. Clough, Tessa R. Young, Emma Tarrant, Andrew J. P. Scott, Peter T. Chivers, Arthur Glasfeld, Nigel J. Robinson |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56199-w |
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