Arylpyrrole derivatives as anti-malarial agents- in vivo and in silico investigations

Arylpyrrole derivatives as anti-malarial agents- in vivo and in silico investigations

Abstract Plasmodium falciparum, has been found to be resistant to practically every antimalarial medication now on the market. Consequently, it is imperative to develop new antimalarial agents with novel mechanistic pathway to stem the tide of P. falciparum resistance. In this study, the capacity of...

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Bibliographic Details
Main Authors: Chiamaka Gift Iwegbulam, Oluwatoba Emmanuel Oyeneyin, Ogunyemi Oderinlo, Damilola Alex Omoboyowa, Niyi Adelakun, Nash Oyekanmi, Idowu Olaposi Omotuyi
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Chemistry
Subjects:
Arylpyrroles
Malaria
Molecular docking
Molecular dynamics simulation
In vivo
Online Access:https://doi.org/10.1007/s44371-025-00176-1
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