Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment
Carotid-to-radial pulse wave velocity (PWVcr) has been proposed to evaluate endothelial function. However, the measurement of PWVcr is not without limitations. A new simple approach could have wide application. Stiffness index (SI) is obtained by analysis of the peripheral pulse wave and gives repro...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/490742 |
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| author | Juan Torrado Daniel Bia Yanina Zócalo Ignacio Farro Federico Farro Ricardo L. Armentano |
| author_facet | Juan Torrado Daniel Bia Yanina Zócalo Ignacio Farro Federico Farro Ricardo L. Armentano |
| author_sort | Juan Torrado |
| collection | DOAJ |
| description | Carotid-to-radial pulse wave velocity (PWVcr) has been proposed to evaluate endothelial function. However, the measurement of PWVcr is not without limitations. A new simple approach could have wide application. Stiffness index (SI) is obtained by analysis of the peripheral pulse wave and gives reproducible information about stiffness of large arteries. This study assessed the effects of hyperemia on SI and compared it with PWVcr in 14 healthy subjects. Both were measured at rest and during 8 minutes after ischemia. SI temporal course was determined. At 1 minute, SI and PWVcr decreased (5.58±0.24 to 5.34±0.23 m/s, P<0.05; 7.8±1.0 to 7.2±0.9 m/s; P<0.05, resp.). SI was positively related to PWVcr in baseline (r=0.62
, P<0.05), at 1 minute (r=0.79, P<0.05), and during the whole experimental session (r=0.52, P<0.05). Conclusion. Hyperemia significantly decreases SI in healthy subjects. SI was related to PWVcr and could be used to facilitate the evaluation of hyperemia-related changes in arterial stiffness. |
| format | Article |
| id | doaj-art-b5d4f2fc2ebb46808b8d97f878136831 |
| institution | Kabale University |
| issn | 2090-2824 2090-2832 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Vascular Medicine |
| spelling | doaj-art-b5d4f2fc2ebb46808b8d97f8781368312025-02-03T06:00:23ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322012-01-01201210.1155/2012/490742490742Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity AssessmentJuan Torrado0Daniel Bia1Yanina Zócalo2Ignacio Farro3Federico Farro4Ricardo L. Armentano5Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayPhysiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayPhysiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayPhysiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayPhysiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayPhysiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Republic University, General Flores 2125, 11800 Montevideo, UruguayCarotid-to-radial pulse wave velocity (PWVcr) has been proposed to evaluate endothelial function. However, the measurement of PWVcr is not without limitations. A new simple approach could have wide application. Stiffness index (SI) is obtained by analysis of the peripheral pulse wave and gives reproducible information about stiffness of large arteries. This study assessed the effects of hyperemia on SI and compared it with PWVcr in 14 healthy subjects. Both were measured at rest and during 8 minutes after ischemia. SI temporal course was determined. At 1 minute, SI and PWVcr decreased (5.58±0.24 to 5.34±0.23 m/s, P<0.05; 7.8±1.0 to 7.2±0.9 m/s; P<0.05, resp.). SI was positively related to PWVcr in baseline (r=0.62 , P<0.05), at 1 minute (r=0.79, P<0.05), and during the whole experimental session (r=0.52, P<0.05). Conclusion. Hyperemia significantly decreases SI in healthy subjects. SI was related to PWVcr and could be used to facilitate the evaluation of hyperemia-related changes in arterial stiffness.http://dx.doi.org/10.1155/2012/490742 |
| spellingShingle | Juan Torrado Daniel Bia Yanina Zócalo Ignacio Farro Federico Farro Ricardo L. Armentano Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment International Journal of Vascular Medicine |
| title | Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment |
| title_full | Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment |
| title_fullStr | Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment |
| title_full_unstemmed | Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment |
| title_short | Hyperemia-Related Changes in Arterial Stiffness: Comparison between Pulse Wave Velocity and Stiffness Index in the Vascular Reactivity Assessment |
| title_sort | hyperemia related changes in arterial stiffness comparison between pulse wave velocity and stiffness index in the vascular reactivity assessment |
| url | http://dx.doi.org/10.1155/2012/490742 |
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