Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review

EBUS-TBNA is the most common interventional pulmonology procedure performed globally and remains the cornerstone of the diagnosis and staging not only of lung cancer but also for other neoplastic, inflammatory, and infective pathologies of the mediastinum. Infective complications of EBUS-TBNA are un...

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Main Authors: Pinelopi Bosgana, Dimitrios Ampazis, Vasileios Vlachakos, Argyrios Tzouvelekis, Fotios Sampsonas
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/2/145
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author Pinelopi Bosgana
Dimitrios Ampazis
Vasileios Vlachakos
Argyrios Tzouvelekis
Fotios Sampsonas
author_facet Pinelopi Bosgana
Dimitrios Ampazis
Vasileios Vlachakos
Argyrios Tzouvelekis
Fotios Sampsonas
author_sort Pinelopi Bosgana
collection DOAJ
description EBUS-TBNA is the most common interventional pulmonology procedure performed globally and remains the cornerstone of the diagnosis and staging not only of lung cancer but also for other neoplastic, inflammatory, and infective pathologies of the mediastinum. Infective complications of EBUS-TBNA are underreported in the literature, but the constantly rising incidence of lung cancer is leading to an increasing number of EBUS-TBNA procedures and, therefore, to a significant number of infective complications, even 4 weeks following the procedure. In this review we attempt to summarize the risk factors related to these infective complications, along with useful biomarkers that can be used to identify patients that might develop infective complications, to facilitate the prediction or even prompt treatment of these.
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id doaj-art-b5d1d036716749c484f26b4c07ca4cdf
institution Kabale University
issn 2075-4418
language English
publishDate 2025-01-01
publisher MDPI AG
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series Diagnostics
spelling doaj-art-b5d1d036716749c484f26b4c07ca4cdf2025-01-24T13:28:53ZengMDPI AGDiagnostics2075-44182025-01-0115214510.3390/diagnostics15020145Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise ReviewPinelopi Bosgana0Dimitrios Ampazis1Vasileios Vlachakos2Argyrios Tzouvelekis3Fotios Sampsonas4Department of Pathology, General Hospital of Patras, 26504 Patras, GreeceRespiratory Department Cavan & Monoghan Hospital, HSE/RCSI Hospital Group, H12Y7W1 Cavan, IrelandBioclinic General Hospital of Athens, Henry Dunant Hospital Center, 11526 Athens, GreeceDepartment of Respiratory Medicine, Medical School, University of Patras, 26504 Patras, GreeceDepartment of Respiratory Medicine, Medical School, University of Patras, 26504 Patras, GreeceEBUS-TBNA is the most common interventional pulmonology procedure performed globally and remains the cornerstone of the diagnosis and staging not only of lung cancer but also for other neoplastic, inflammatory, and infective pathologies of the mediastinum. Infective complications of EBUS-TBNA are underreported in the literature, but the constantly rising incidence of lung cancer is leading to an increasing number of EBUS-TBNA procedures and, therefore, to a significant number of infective complications, even 4 weeks following the procedure. In this review we attempt to summarize the risk factors related to these infective complications, along with useful biomarkers that can be used to identify patients that might develop infective complications, to facilitate the prediction or even prompt treatment of these.https://www.mdpi.com/2075-4418/15/2/145EBUS-TBNAinfective complicationsbiomarkersinterleukin-6procalcitonin
spellingShingle Pinelopi Bosgana
Dimitrios Ampazis
Vasileios Vlachakos
Argyrios Tzouvelekis
Fotios Sampsonas
Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
Diagnostics
EBUS-TBNA
infective complications
biomarkers
interleukin-6
procalcitonin
title Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
title_full Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
title_fullStr Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
title_full_unstemmed Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
title_short Infective Complications of Endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) and Clinical Biomarkers: A Concise Review
title_sort infective complications of endobronchial ultrasound transbronchial needle aspiration ebus tbna and clinical biomarkers a concise review
topic EBUS-TBNA
infective complications
biomarkers
interleukin-6
procalcitonin
url https://www.mdpi.com/2075-4418/15/2/145
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