Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV
To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/379097 |
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| author | Sheng-Hwu Hsieh Szu-Tah Chen Chuen Hsueh Tzu-Chieh Chao Jen-Der Lin |
| author_facet | Sheng-Hwu Hsieh Szu-Tah Chen Chuen Hsueh Tzu-Chieh Chao Jen-Der Lin |
| author_sort | Sheng-Hwu Hsieh |
| collection | DOAJ |
| description | To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a higher incidence of male patients in the N1b group. There were 65 from 316 female (20.6%) and 49 from 120 male (40.8%) patients who had a postoperative disease progression. A total of 55 (12.6%) patients died of thyroid cancer. Male patients showed a higher thyroid cancer mortality than the females. Multiple regression analysis showed that male gender was an independent risk factor for cancer recurrence and mortality. Male patients with TNM stages II to IV of papillary thyroid cancer need to adopt aggressive surgical and postoperative 131I therapy. |
| format | Article |
| id | doaj-art-b5ce8495fdd14af79aeb8945d027e606 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-b5ce8495fdd14af79aeb8945d027e6062025-02-03T01:32:46ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/379097379097Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IVSheng-Hwu Hsieh0Szu-Tah Chen1Chuen Hsueh2Tzu-Chieh Chao3Jen-Der Lin4Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, TaiwanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, TaiwanDepartment of Pathology, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, TaiwanDepartment of General Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, TaiwanDivision of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Linkou 333, TaiwanTo investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a higher incidence of male patients in the N1b group. There were 65 from 316 female (20.6%) and 49 from 120 male (40.8%) patients who had a postoperative disease progression. A total of 55 (12.6%) patients died of thyroid cancer. Male patients showed a higher thyroid cancer mortality than the females. Multiple regression analysis showed that male gender was an independent risk factor for cancer recurrence and mortality. Male patients with TNM stages II to IV of papillary thyroid cancer need to adopt aggressive surgical and postoperative 131I therapy.http://dx.doi.org/10.1155/2012/379097 |
| spellingShingle | Sheng-Hwu Hsieh Szu-Tah Chen Chuen Hsueh Tzu-Chieh Chao Jen-Der Lin Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV International Journal of Endocrinology |
| title | Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV |
| title_full | Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV |
| title_fullStr | Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV |
| title_full_unstemmed | Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV |
| title_short | Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV |
| title_sort | gender specific variation in the prognosis of papillary thyroid cancer tnm stages ii to iv |
| url | http://dx.doi.org/10.1155/2012/379097 |
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