Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review
The metastasis of breast cancer to the colon is a rare occurrence, especially in the presence of changes in estrogen and progesterone receptors. To date, literature has only reported two cases of invasive ductal carcinoma and two cases of invasive lobular carcinoma metastasizing to the colon with co...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1391393/full |
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| author | Huimeng Li Liying Yang Xiqiang Sun Zhuquan Wang Shuangwei Qin Chengcheng Li Gongwu Liu Fengming Xie Weiwei Gao |
| author_facet | Huimeng Li Liying Yang Xiqiang Sun Zhuquan Wang Shuangwei Qin Chengcheng Li Gongwu Liu Fengming Xie Weiwei Gao |
| author_sort | Huimeng Li |
| collection | DOAJ |
| description | The metastasis of breast cancer to the colon is a rare occurrence, especially in the presence of changes in estrogen and progesterone receptors. To date, literature has only reported two cases of invasive ductal carcinoma and two cases of invasive lobular carcinoma metastasizing to the colon with concurrent changes in hormone receptors. This report describes a 65-year-old woman with a history of left breast cancer, who presented with symptoms of bloody stools and abdominal pain. CT and colonoscopy results revealed a malignant tumor in the ascending colon, and the patient underwent surgery. Pathological results post-surgery indicated changes in hormone receptors, differing from the previous breast cancer pathology, ultimately leading to the diagnosis of breast cancer metastasis to the colon. The patient was found to have liver metastasis 14 months after right hemicolectomy, and systemic metastases in various locations were discovered at the 19-month mark. |
| format | Article |
| id | doaj-art-b5bc3cf70d11444d9335b772b88489e0 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-b5bc3cf70d11444d9335b772b88489e02025-01-29T05:21:23ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011410.3389/fonc.2024.13913931391393Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature reviewHuimeng Li0Liying Yang1Xiqiang Sun2Zhuquan Wang3Shuangwei Qin4Chengcheng Li5Gongwu Liu6Fengming Xie7Weiwei Gao8Department of Thyroid and Breast Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Pathology, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Hepatobiliary Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Thyroid and Breast Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Thyroid and Breast Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Thyroid and Breast Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Hepatobiliary Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Thyroid and Breast Surgery, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe State, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaDepartment of Rheumatology and Immunology, Southern Central Hospital of Yunnan Province, The First People’s Hospital of Honghe state, Honghe Hospital Affiliated to Kunming Medical University, Gejiu, Yunnan, ChinaThe metastasis of breast cancer to the colon is a rare occurrence, especially in the presence of changes in estrogen and progesterone receptors. To date, literature has only reported two cases of invasive ductal carcinoma and two cases of invasive lobular carcinoma metastasizing to the colon with concurrent changes in hormone receptors. This report describes a 65-year-old woman with a history of left breast cancer, who presented with symptoms of bloody stools and abdominal pain. CT and colonoscopy results revealed a malignant tumor in the ascending colon, and the patient underwent surgery. Pathological results post-surgery indicated changes in hormone receptors, differing from the previous breast cancer pathology, ultimately leading to the diagnosis of breast cancer metastasis to the colon. The patient was found to have liver metastasis 14 months after right hemicolectomy, and systemic metastases in various locations were discovered at the 19-month mark.https://www.frontiersin.org/articles/10.3389/fonc.2024.1391393/fullcolon metastasisprogesterone receptorestrogen receptornon-specific types of breast cancerbreast cancer |
| spellingShingle | Huimeng Li Liying Yang Xiqiang Sun Zhuquan Wang Shuangwei Qin Chengcheng Li Gongwu Liu Fengming Xie Weiwei Gao Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review Frontiers in Oncology colon metastasis progesterone receptor estrogen receptor non-specific types of breast cancer breast cancer |
| title | Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review |
| title_full | Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review |
| title_fullStr | Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review |
| title_full_unstemmed | Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review |
| title_short | Changes in hormone receptor when breast cancer metastasizes to the colon: case report and literature review |
| title_sort | changes in hormone receptor when breast cancer metastasizes to the colon case report and literature review |
| topic | colon metastasis progesterone receptor estrogen receptor non-specific types of breast cancer breast cancer |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1391393/full |
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