Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy
Many endoscopic imaging modalities have been developed and introduced into clinical practice to enhance the diagnostic capabilities of upper endoscopy. In the past, detection of dysplasia and carcinoma of esophagus had been dependent on biopsies taken during standard white-light endoscopy (WLE). Rec...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2012/493961 |
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| author | Helga Bertani Flavia Pigò Emanuele Dabizzi Marzio Frazzoni Vincenzo Giorgio Mirante Mauro Manno Raffaele Manta Rita Conigliaro |
| author_facet | Helga Bertani Flavia Pigò Emanuele Dabizzi Marzio Frazzoni Vincenzo Giorgio Mirante Mauro Manno Raffaele Manta Rita Conigliaro |
| author_sort | Helga Bertani |
| collection | DOAJ |
| description | Many endoscopic imaging modalities have been developed and introduced into clinical practice to enhance the diagnostic capabilities of upper endoscopy. In the past, detection of dysplasia and carcinoma of esophagus had been dependent on biopsies taken during standard white-light endoscopy (WLE). Recently high-resolution (HR) endoscopy enables us to visualize esophageal mucosa but resolution for glandular structures and cells is still low. Probe-based confocal laser endomicroscopy (pCLE) is a new promising diagnostic technique by which details of glandular and vascular structures of mucosal layer can be observed. However, the clinical utility of this new diagnostic tool has not yet been fully explored in a clinical setting. In this paper we will highlight this new technique for detection of esophageal dysplasia and carcinoma from a clinical practice perspective. |
| format | Article |
| id | doaj-art-b5afc364a0534675bdb00f702c207aca |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-b5afc364a0534675bdb00f702c207aca2025-02-03T06:11:43ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/493961493961Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser EndomicroscopyHelga Bertani0Flavia Pigò1Emanuele Dabizzi2Marzio Frazzoni3Vincenzo Giorgio Mirante4Mauro Manno5Raffaele Manta6Rita Conigliaro7Endoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyEndoscopy Unit, Nuovo Ospedale Civile S. Agostino Estense, Via Giardini 1355, Baggiovara, 41126 Modena, ItalyMany endoscopic imaging modalities have been developed and introduced into clinical practice to enhance the diagnostic capabilities of upper endoscopy. In the past, detection of dysplasia and carcinoma of esophagus had been dependent on biopsies taken during standard white-light endoscopy (WLE). Recently high-resolution (HR) endoscopy enables us to visualize esophageal mucosa but resolution for glandular structures and cells is still low. Probe-based confocal laser endomicroscopy (pCLE) is a new promising diagnostic technique by which details of glandular and vascular structures of mucosal layer can be observed. However, the clinical utility of this new diagnostic tool has not yet been fully explored in a clinical setting. In this paper we will highlight this new technique for detection of esophageal dysplasia and carcinoma from a clinical practice perspective.http://dx.doi.org/10.1155/2012/493961 |
| spellingShingle | Helga Bertani Flavia Pigò Emanuele Dabizzi Marzio Frazzoni Vincenzo Giorgio Mirante Mauro Manno Raffaele Manta Rita Conigliaro Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy Gastroenterology Research and Practice |
| title | Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy |
| title_full | Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy |
| title_fullStr | Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy |
| title_full_unstemmed | Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy |
| title_short | Advances in Endoscopic Visualization of Barrett’s Esophagus: The Role of Confocal Laser Endomicroscopy |
| title_sort | advances in endoscopic visualization of barrett s esophagus the role of confocal laser endomicroscopy |
| url | http://dx.doi.org/10.1155/2012/493961 |
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