Maternal plasma cell-free RNA as a predictive test for fetal lung maturation

Maternal plasma cell-free RNA as a predictive test for fetal lung maturation

Abstract Background A lack of tests to assess fetal development impacts decision making around antenatal steroid use in women at risk of preterm birth. We analyzed the expression of 21 cfRNA targets related to human fetal lung maturation. Discovery studies were performed using maternal and fetal she...

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Main Authors: Sean W. D. Carter, Kay Yi Michelle Seah, Si En Poh, Winston Koh, Haruo Usuda, Erin L. Johnson, Yusaku Kumagai, Tsukasa Takahashi, Lara J. Monteiro, Reyna Peñailillo, Gino Nardocci, Hannah R. S. Watson, Masatoshi Saito, Mahesh A. Choolani, Sebastián E. Illanes, Matthew W. Kemp
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Cell-free RNA
Preterm birth
Lung maturation
Antenatal corticosteroids
Predictive test
Gene expression
Online Access:https://doi.org/10.1186/s12916-025-04256-y
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