An in-depth study of indolone derivatives as potential lung cancer treatment

An in-depth study of indolone derivatives as potential lung cancer treatment

Abstract Lung cancer is a type of cancer that begins in the lungs and is one of the leading causes of cancer-related deaths worldwide. Herein an attempt to explore the relationship between the properties of indolone derivatives and their anticancer activity was investigated, implementing in silico a...

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Bibliographic Details
Main Authors: Mohammed Er-rajy, Mohamed El fadili, Radwan Alnajjar, Sara Zarougui, Somdutt Mujwar, Khalil Azzaoui, Hatem A. Abuelizz, Belkheir Hammouti, Menana Elhallaoui
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
PI3K-PDK1-AKT pathway
DFT study
Molecular docking
Molecular dynamic
ADMET properties
Online Access:https://doi.org/10.1038/s41598-025-85707-7
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https://doi.org/10.1038/s41598-025-85707-7

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