Role of Perinatal Stem Cell Secretome as Potential Therapy for Muscular Dystrophies

Role of Perinatal Stem Cell Secretome as Potential Therapy for Muscular Dystrophies

Inflammation mechanisms play a critical role in muscle homeostasis, and in Muscular Dystrophies (MDs), the myofiber damage triggers chronic inflammation which significantly controls the disease progression. Immunomodulatory strategies able to target inflammatory pathways and mitigate the immune-medi...

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Bibliographic Details
Main Authors: Serafina Pacilio, Sara Lombardi, Roberta Costa, Francesca Paris, Giovannamaria Petrocelli, Pasquale Marrazzo, Giovanna Cenacchi, Francesco Alviano
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Biomedicines
Subjects:
muscular dystrophy
mesenchymal stem cells
perinatal secretome
cell-free therapy
extracellular vesicles
immunomodulation
Online Access:https://www.mdpi.com/2227-9059/13/2/458
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