Inflammation and Hypertension: Are There Regional Differences?

Hypertension is a chronic disease with global prevalence and incidence rapidly increasing in low and medium income countries. The surveillance of cardiovascular risk factors, such as hypertension, is a global health priority in order to estimate the burden and trends, to appropriately direct resourc...

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Main Authors: Patricio López-Jaramillo, Carlos Velandia-Carrillo, Julie Álvarez-Camacho, Daniel Dylan Cohen, Tatiana Sánchez-Solano, Gabriela Castillo-López
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2013/492094
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author Patricio López-Jaramillo
Carlos Velandia-Carrillo
Julie Álvarez-Camacho
Daniel Dylan Cohen
Tatiana Sánchez-Solano
Gabriela Castillo-López
author_facet Patricio López-Jaramillo
Carlos Velandia-Carrillo
Julie Álvarez-Camacho
Daniel Dylan Cohen
Tatiana Sánchez-Solano
Gabriela Castillo-López
author_sort Patricio López-Jaramillo
collection DOAJ
description Hypertension is a chronic disease with global prevalence and incidence rapidly increasing in low and medium income countries. The surveillance of cardiovascular risk factors, such as hypertension, is a global health priority in order to estimate the burden and trends, to appropriately direct resources, and to measure the effect of interventions. We propose here that the adoption of Western lifestyles in low and middle incomes countries has dramatically increased the prevalence of abdominal obesity, which is the main source of proinflammatory cytokines, and that the vascular systemic inflammation produced by adipose tissue contributes to the development of hypertension. The concentration of proinflammatory cytokines is higher in the Latin American population than that reported in developed countries, suggesting a higher susceptibility to develop systemic low-degree inflammation at a given level of abdominal obesity. These particularities are important to be considered when planning resources for health care programs. Moreover, studying these singularities may provide a better understanding of the causes of the burden of cardiovascular risk factors and the remarkable variability in the prevalence of these medical conditions within and between countries.
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institution Kabale University
issn 2090-0384
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language English
publishDate 2013-01-01
publisher Wiley
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series International Journal of Hypertension
spelling doaj-art-b587a1158963412aa623656c18ed094d2025-02-03T01:10:08ZengWileyInternational Journal of Hypertension2090-03842090-03922013-01-01201310.1155/2013/492094492094Inflammation and Hypertension: Are There Regional Differences?Patricio López-Jaramillo0Carlos Velandia-Carrillo1Julie Álvarez-Camacho2Daniel Dylan Cohen3Tatiana Sánchez-Solano4Gabriela Castillo-López5Fundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle (FOSCAL), Floridablanca, Santander, ColombiaFundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle (FOSCAL), Floridablanca, Santander, ColombiaFundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle (FOSCAL), Floridablanca, Santander, ColombiaFundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle (FOSCAL), Floridablanca, Santander, ColombiaFundación Oftalmológica de Santander-Clínica Carlos Ardila Lulle (FOSCAL), Floridablanca, Santander, ColombiaFacultad de Medecina, Pontificia Universidad Católica del Ecuador (PUCE), Av. 12 de Octubre 1076 y Roca, 17 01 21 84 Quito, EcuadorHypertension is a chronic disease with global prevalence and incidence rapidly increasing in low and medium income countries. The surveillance of cardiovascular risk factors, such as hypertension, is a global health priority in order to estimate the burden and trends, to appropriately direct resources, and to measure the effect of interventions. We propose here that the adoption of Western lifestyles in low and middle incomes countries has dramatically increased the prevalence of abdominal obesity, which is the main source of proinflammatory cytokines, and that the vascular systemic inflammation produced by adipose tissue contributes to the development of hypertension. The concentration of proinflammatory cytokines is higher in the Latin American population than that reported in developed countries, suggesting a higher susceptibility to develop systemic low-degree inflammation at a given level of abdominal obesity. These particularities are important to be considered when planning resources for health care programs. Moreover, studying these singularities may provide a better understanding of the causes of the burden of cardiovascular risk factors and the remarkable variability in the prevalence of these medical conditions within and between countries.http://dx.doi.org/10.1155/2013/492094
spellingShingle Patricio López-Jaramillo
Carlos Velandia-Carrillo
Julie Álvarez-Camacho
Daniel Dylan Cohen
Tatiana Sánchez-Solano
Gabriela Castillo-López
Inflammation and Hypertension: Are There Regional Differences?
International Journal of Hypertension
title Inflammation and Hypertension: Are There Regional Differences?
title_full Inflammation and Hypertension: Are There Regional Differences?
title_fullStr Inflammation and Hypertension: Are There Regional Differences?
title_full_unstemmed Inflammation and Hypertension: Are There Regional Differences?
title_short Inflammation and Hypertension: Are There Regional Differences?
title_sort inflammation and hypertension are there regional differences
url http://dx.doi.org/10.1155/2013/492094
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AT carlosvelandiacarrillo inflammationandhypertensionarethereregionaldifferences
AT juliealvarezcamacho inflammationandhypertensionarethereregionaldifferences
AT danieldylancohen inflammationandhypertensionarethereregionaldifferences
AT tatianasanchezsolano inflammationandhypertensionarethereregionaldifferences
AT gabrielacastillolopez inflammationandhypertensionarethereregionaldifferences