Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents

Discovery of Quinazolone Pyridiniums as Potential Broad-Spectrum Antibacterial Agents

The overprescription of antibiotics in medicine and agriculture has accelerated the development and spread of antibiotic resistance in bacteria, which severely limits the arsenal available to clinicians for treating bacterial infections. This work discovered a new class of heteroarylcyanovinyl quina...

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Bibliographic Details
Main Authors: Jie Dai, Qianyue Li, Ziyi Li, Zhonglin Zang, Yan Luo, Chenghe Zhou
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Molecules
Subjects:
quinazolone
pyridinium
resistance
antibacterial
PBP2a
Online Access:https://www.mdpi.com/1420-3049/30/2/243
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