Bisphenol A and Metabolic Syndrome: Results from NHANES
Background. Bisphenol A (BPA) is detected in the urine of >95% of US adults. Recent evidence from population-based studies suggests that BPA is associated with individual components for metabolic syndrome (MetS). However, no previous study has examined the direct association between BPA and MetS....
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/598180 |
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| author | Srinivas Teppala Suresh Madhavan Anoop Shankar |
| author_facet | Srinivas Teppala Suresh Madhavan Anoop Shankar |
| author_sort | Srinivas Teppala |
| collection | DOAJ |
| description | Background. Bisphenol A (BPA) is detected in the urine of >95% of US adults. Recent evidence from population-based studies suggests that BPA is associated with individual components for metabolic syndrome (MetS). However, no previous study has examined the direct association between BPA and MetS. Methods. We examined 2,104 participants from the National Health and Nutrition Examination Survey 2003–2008. The main outcome was the presence of MetS (n=741). Results. Increasing levels of urinary BPA were positively associated with MetS, independent of confounders such as age, gender, race/ethnicity, smoking, alcohol intake, physical activity, and urinary creatinine. Compared to tertile 1 (referent), the multivariable adjusted odds ratio (95% confidence interval) of MetS in tertile 3 was 1.51 (1.07–2.12); P-trend was 0.02. Conclusions. Urinary BPA levels are positively associated with MetS, in a representative sample of US adults and independent of traditional risk factors for MetS. Future, prospective studies are needed to confirm our findings. |
| format | Article |
| id | doaj-art-b55c4128dd7e4601977dac9455933e36 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-b55c4128dd7e4601977dac9455933e362025-02-03T01:23:17ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/598180598180Bisphenol A and Metabolic Syndrome: Results from NHANESSrinivas Teppala0Suresh Madhavan1Anoop Shankar2Department of Epidemiology, West Virginia University School of Public Health, P.O. Box 9190, Morgantown, WV 26506-9190, USADepartment of Pharmaceutical Systems and Policy, West Virginia University School of Pharmacy, Morgantown, WV 26506, USADepartment of Epidemiology, West Virginia University School of Public Health, P.O. Box 9190, Morgantown, WV 26506-9190, USABackground. Bisphenol A (BPA) is detected in the urine of >95% of US adults. Recent evidence from population-based studies suggests that BPA is associated with individual components for metabolic syndrome (MetS). However, no previous study has examined the direct association between BPA and MetS. Methods. We examined 2,104 participants from the National Health and Nutrition Examination Survey 2003–2008. The main outcome was the presence of MetS (n=741). Results. Increasing levels of urinary BPA were positively associated with MetS, independent of confounders such as age, gender, race/ethnicity, smoking, alcohol intake, physical activity, and urinary creatinine. Compared to tertile 1 (referent), the multivariable adjusted odds ratio (95% confidence interval) of MetS in tertile 3 was 1.51 (1.07–2.12); P-trend was 0.02. Conclusions. Urinary BPA levels are positively associated with MetS, in a representative sample of US adults and independent of traditional risk factors for MetS. Future, prospective studies are needed to confirm our findings.http://dx.doi.org/10.1155/2012/598180 |
| spellingShingle | Srinivas Teppala Suresh Madhavan Anoop Shankar Bisphenol A and Metabolic Syndrome: Results from NHANES International Journal of Endocrinology |
| title | Bisphenol A and Metabolic Syndrome: Results from NHANES |
| title_full | Bisphenol A and Metabolic Syndrome: Results from NHANES |
| title_fullStr | Bisphenol A and Metabolic Syndrome: Results from NHANES |
| title_full_unstemmed | Bisphenol A and Metabolic Syndrome: Results from NHANES |
| title_short | Bisphenol A and Metabolic Syndrome: Results from NHANES |
| title_sort | bisphenol a and metabolic syndrome results from nhanes |
| url | http://dx.doi.org/10.1155/2012/598180 |
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