Study on Molecular Recognition between Euphorbia Factor L713283 and β-Tubulin via Molecular Simulation Methods
Euphorbia factor L713283 is a new lathyrane diterpene isolated from Euphorbia lathyris and shows strong anticancer activity. By using molecular similarity analysis, β-tubulin was identified as one of the possible targets of L713283. We further investigated the binding modes of L713283 with β-tubulin...
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Main Authors: | Shan Chang, Hong-qiu He, Ren Kong, Zhen-jian Xie, Jian-ping Hu |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | Journal of Chemistry |
Online Access: | http://dx.doi.org/10.1155/2015/879238 |
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