Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP?
Over a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complic...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2021/9969825 |
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| author | Jan Stovicek Stepan Hlava Radan Keil Jiri Drabek Jindra Lochmannova Petra Koptová Martin Wasserbauer Barbora Frybova Jiri Snajdauf Radana Kotalova Michal Rygl |
| author_facet | Jan Stovicek Stepan Hlava Radan Keil Jiri Drabek Jindra Lochmannova Petra Koptová Martin Wasserbauer Barbora Frybova Jiri Snajdauf Radana Kotalova Michal Rygl |
| author_sort | Jan Stovicek |
| collection | DOAJ |
| description | Over a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complication rate was 13.7%. Hyperamylasemia occurred in 12.9%. More severe complications were rare‐0.8% of ERCP procedure. There were no cases of postprocedural pancreatitis or death. Our study has proved that ERCP is a safe and reliable method in this age group. Its high specificity and negative predictive value for extrahepatic biliary atresia can prevent unnecessary surgeries in patients with normal bile ducts or endoscopically treatable pathologies. |
| format | Article |
| id | doaj-art-b5361511713f450cbfb64614c2a9a3f0 |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-b5361511713f450cbfb64614c2a9a3f02025-02-03T01:04:33ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972021-01-01202110.1155/2021/99698259969825Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP?Jan Stovicek0Stepan Hlava1Radan Keil2Jiri Drabek3Jindra Lochmannova4Petra Koptová5Martin Wasserbauer6Barbora Frybova7Jiri Snajdauf8Radana Kotalova9Michal Rygl10Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Pediatry, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicDepartment of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech RepublicOver a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complication rate was 13.7%. Hyperamylasemia occurred in 12.9%. More severe complications were rare‐0.8% of ERCP procedure. There were no cases of postprocedural pancreatitis or death. Our study has proved that ERCP is a safe and reliable method in this age group. Its high specificity and negative predictive value for extrahepatic biliary atresia can prevent unnecessary surgeries in patients with normal bile ducts or endoscopically treatable pathologies.http://dx.doi.org/10.1155/2021/9969825 |
| spellingShingle | Jan Stovicek Stepan Hlava Radan Keil Jiri Drabek Jindra Lochmannova Petra Koptová Martin Wasserbauer Barbora Frybova Jiri Snajdauf Radana Kotalova Michal Rygl Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? Canadian Journal of Gastroenterology and Hepatology |
| title | Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? |
| title_full | Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? |
| title_fullStr | Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? |
| title_full_unstemmed | Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? |
| title_short | Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP? |
| title_sort | conjugated hyperbilirubinemia in infants is there still a role for ercp |
| url | http://dx.doi.org/10.1155/2021/9969825 |
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