FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system

Abstract Background Targeted therapy is an effective strategy for the treatment of advanced and metastatic pancreatic cancer, one of the leading causes for cancer-related death worldwide. To address the limitations of existing targeted drugs, there is an urgently need to find novel targets and thera...

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Bibliographic Details
Main Authors: Xiaolong Liu, Xueyan Zhang, Tingyu Zeng, Yali Chen, Liu Ye, Shuping Wang, Yulan Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06304-w
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