Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study
Abstract Objective To explore the factors that affect the efficacy of knee replacement surgery in hemophiliacs. Methods A retrospective analysis was conducted on 87 patients with hemophilia (PWH) (117knees) who underwent knee arthroplasty in our hospital from January 2012 to December 2020 (mean foll...
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BMC
2025-02-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-025-08354-z |
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| author | Hongyu Jiang Xueke Chang Fubin Yu Ming Zhang Yifan Liu Jianzhi Man Kangshu Guo Hongzheng Meng Wenqiang Zhang |
| author_facet | Hongyu Jiang Xueke Chang Fubin Yu Ming Zhang Yifan Liu Jianzhi Man Kangshu Guo Hongzheng Meng Wenqiang Zhang |
| author_sort | Hongyu Jiang |
| collection | DOAJ |
| description | Abstract Objective To explore the factors that affect the efficacy of knee replacement surgery in hemophiliacs. Methods A retrospective analysis was conducted on 87 patients with hemophilia (PWH) (117knees) who underwent knee arthroplasty in our hospital from January 2012 to December 2020 (mean follow-up 70.8 ± 22 months). General information, hemophilia information, surgical information, follow-up information and psychological assessment information were collected. The knee joint efficacy was evaluated using the Hospital for Special Surgery (HSS) knee score, the American Knee Society’s Clinical (KSC) and Functional (KSF) scores, flexion contracture degree (FC), range of motion (ROM), and wound healing. The excellent and poor groups were divided based on these factors. Logistic regression analysis was used to analyze factors that may affect the knee joint efficacy of patients. Results Seventy-four cases of excellent knee joints and 43 cases of poor knee joints were included. Single factor analysis: The pre-ROM, SF-12MCS, HSS, KSF, and KSC of the excellent group were significantly higher than those of the poor group (P < 0.05); the Hamilton Depression Scale (HAMD), Preoperative Visual Analogue Scale(Pre-VAS), pre-FC degree of the excellent group were significantly lower than those of the poor group (P < 0.05). The proportion of patients undergoing Simultaneous bilateral knee replacement, severe hemophilia, and quadricepsplasty during surgery in the excellent group was significantly lower than that in the poor group (P < 0.05). Logistic regression: Pre-ROM and Simultaneous bilateral knee replacement are independent risk factors affecting knee joint efficacy. Pre-ROM is positively correlated with knee joint efficacy, while Simultaneous bilateral knee replacement is negatively correlated. Conclusion In PWH, the efficacy of knee replacement surgery is related to preoperative ROM and Simultaneous bilateral knee replacement. Better preoperative knee joint mobility is associated with improved outcomes, whereas Simultaneous bilateral knee replacement negatively impacts surgical efficacy. |
| format | Article |
| id | doaj-art-b51e0abe3e704605bf8560234330db3b |
| institution | Kabale University |
| issn | 1471-2474 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj-art-b51e0abe3e704605bf8560234330db3b2025-02-02T12:05:26ZengBMCBMC Musculoskeletal Disorders1471-24742025-02-012611910.1186/s12891-025-08354-zInfluencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective studyHongyu Jiang0Xueke Chang1Fubin Yu2Ming Zhang3Yifan Liu4Jianzhi Man5Kangshu Guo6Hongzheng Meng7Wenqiang Zhang8Shandong First Medical UniversityShandong First Medical UniversityDepartment of Bone and Joint Surgery, Zhangqiu District People’s HospitalDepartment of Bone and Joint Surgery, First Affiliated Hospital of Shandong First Medical UniversityDepartment of Bone and Joint Surgery, First Affiliated Hospital of Shandong First Medical UniversityShandong First Medical UniversityShandong First Medical UniversityDepartment of Bone and Joint Surgery, First Affiliated Hospital of Shandong First Medical UniversityDepartment of Bone and Joint Surgery, First Affiliated Hospital of Shandong First Medical UniversityAbstract Objective To explore the factors that affect the efficacy of knee replacement surgery in hemophiliacs. Methods A retrospective analysis was conducted on 87 patients with hemophilia (PWH) (117knees) who underwent knee arthroplasty in our hospital from January 2012 to December 2020 (mean follow-up 70.8 ± 22 months). General information, hemophilia information, surgical information, follow-up information and psychological assessment information were collected. The knee joint efficacy was evaluated using the Hospital for Special Surgery (HSS) knee score, the American Knee Society’s Clinical (KSC) and Functional (KSF) scores, flexion contracture degree (FC), range of motion (ROM), and wound healing. The excellent and poor groups were divided based on these factors. Logistic regression analysis was used to analyze factors that may affect the knee joint efficacy of patients. Results Seventy-four cases of excellent knee joints and 43 cases of poor knee joints were included. Single factor analysis: The pre-ROM, SF-12MCS, HSS, KSF, and KSC of the excellent group were significantly higher than those of the poor group (P < 0.05); the Hamilton Depression Scale (HAMD), Preoperative Visual Analogue Scale(Pre-VAS), pre-FC degree of the excellent group were significantly lower than those of the poor group (P < 0.05). The proportion of patients undergoing Simultaneous bilateral knee replacement, severe hemophilia, and quadricepsplasty during surgery in the excellent group was significantly lower than that in the poor group (P < 0.05). Logistic regression: Pre-ROM and Simultaneous bilateral knee replacement are independent risk factors affecting knee joint efficacy. Pre-ROM is positively correlated with knee joint efficacy, while Simultaneous bilateral knee replacement is negatively correlated. Conclusion In PWH, the efficacy of knee replacement surgery is related to preoperative ROM and Simultaneous bilateral knee replacement. Better preoperative knee joint mobility is associated with improved outcomes, whereas Simultaneous bilateral knee replacement negatively impacts surgical efficacy.https://doi.org/10.1186/s12891-025-08354-zPatients with hemophilia (PWH)Knee replacementInfluencing factors |
| spellingShingle | Hongyu Jiang Xueke Chang Fubin Yu Ming Zhang Yifan Liu Jianzhi Man Kangshu Guo Hongzheng Meng Wenqiang Zhang Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study BMC Musculoskeletal Disorders Patients with hemophilia (PWH) Knee replacement Influencing factors |
| title | Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study |
| title_full | Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study |
| title_fullStr | Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study |
| title_full_unstemmed | Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study |
| title_short | Influencing factors of the outcome of patients with haemophilia after knee replacement–a retrospective study |
| title_sort | influencing factors of the outcome of patients with haemophilia after knee replacement a retrospective study |
| topic | Patients with hemophilia (PWH) Knee replacement Influencing factors |
| url | https://doi.org/10.1186/s12891-025-08354-z |
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