CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis

CD226+ B cells in primary Sjögren’s syndrome: a key player in clinical manifestations and disease pathogenesis

IntroductionPrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disorder characterized by lymphocytic infiltration of exocrine glands, leading to sicca symptoms and systemic complications. CD226, a co-stimulatory receptor implicated in the pathogenesis of multiple autoimmune diseases including...

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Bibliographic Details
Main Authors: Ping Zhao, Saizhe Song, Song Zhang, Cheng Peng, Wei Cheng, Xin Chang, Changhao Xie, Zhongli Hu, Cuiping Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
CD226
costimulatory molecule
B cells
cytokines
primary Sjögren’s syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1623774/full
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