The nature of self-medication in Uganda: a systematic review and meta-analysis

Abstract Background In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, and the increasing prevalence of antimicrobial resistance. This systematic review and meta-analysis investigated the prevalence and factors associated wit...

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Main Authors: Danladi Makeri, Priscilla Peter Dilli, Theophilus Pius, Naheem Adekilekun Tijani, Abdullateef Afolabi Opeyemi, Kadai Alhaji Lawan, Shango Patience Emmanuel Jakheng, Reagan Muhwezi, Ambrose Shabohurira, Ibe Michael Usman, Ezera Agwu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-21380-9
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author Danladi Makeri
Priscilla Peter Dilli
Theophilus Pius
Naheem Adekilekun Tijani
Abdullateef Afolabi Opeyemi
Kadai Alhaji Lawan
Shango Patience Emmanuel Jakheng
Reagan Muhwezi
Ambrose Shabohurira
Ibe Michael Usman
Ezera Agwu
author_facet Danladi Makeri
Priscilla Peter Dilli
Theophilus Pius
Naheem Adekilekun Tijani
Abdullateef Afolabi Opeyemi
Kadai Alhaji Lawan
Shango Patience Emmanuel Jakheng
Reagan Muhwezi
Ambrose Shabohurira
Ibe Michael Usman
Ezera Agwu
author_sort Danladi Makeri
collection DOAJ
description Abstract Background In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, and the increasing prevalence of antimicrobial resistance. This systematic review and meta-analysis investigated the prevalence and factors associated with self-medication in Uganda. Methods We searched Scopus, PubMed, and Embase databases, WHO AFRO, UNIPH registries, and Google Scholar search engine from inception to November 2024 using the algorithm “Self-Medication” AND “Uganda”. Twenty-two eligible studies were included while adhering to the preferred reporting items for systematic reviews and meta-analysis (PRISMA). Results A total of 9113 participants were represented across different demographics and regions of Uganda. Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled prevalence of self-medication in Uganda. Antibiotics are the commonly self-medicated drugs and ease of access to medications, perceived cost effectiveness, long hospital waiting time, home storage of drugs (leftovers), and perceptions of minor illnesses were key contributors to self-medication behaviour. Conclusion At least 1 in 2 Ugandans self-medicate and antibiotics constitute the dominant self-medicated drugs compounding the situation in an era of antimicrobial resistance. Awareness campaigns on the dangers of self-medication will be timely.
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spelling doaj-art-b4f145eaba554e029062cb1beaca88dc2025-01-19T12:42:18ZengBMCBMC Public Health1471-24582025-01-0125111110.1186/s12889-025-21380-9The nature of self-medication in Uganda: a systematic review and meta-analysisDanladi Makeri0Priscilla Peter Dilli1Theophilus Pius2Naheem Adekilekun Tijani3Abdullateef Afolabi Opeyemi4Kadai Alhaji Lawan5Shango Patience Emmanuel Jakheng6Reagan Muhwezi7Ambrose Shabohurira8Ibe Michael Usman9Ezera Agwu10Department of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Public Health, School of Allied Health Sciences, Kampala International University-Western CampusDepartment of Medical Laboratory Science, School of Allied Health Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Human Anatomy, Faculty of Biomedical Sciences, Kampala International University-Western CampusDepartment of Microbiology and Immunology, Faculty of Biomedical Sciences, Kampala International University-Western CampusAbstract Background In Uganda, many people self-medicate and the practice raises important questions about access to healthcare, patient choices, and the increasing prevalence of antimicrobial resistance. This systematic review and meta-analysis investigated the prevalence and factors associated with self-medication in Uganda. Methods We searched Scopus, PubMed, and Embase databases, WHO AFRO, UNIPH registries, and Google Scholar search engine from inception to November 2024 using the algorithm “Self-Medication” AND “Uganda”. Twenty-two eligible studies were included while adhering to the preferred reporting items for systematic reviews and meta-analysis (PRISMA). Results A total of 9113 participants were represented across different demographics and regions of Uganda. Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled prevalence of self-medication in Uganda. Antibiotics are the commonly self-medicated drugs and ease of access to medications, perceived cost effectiveness, long hospital waiting time, home storage of drugs (leftovers), and perceptions of minor illnesses were key contributors to self-medication behaviour. Conclusion At least 1 in 2 Ugandans self-medicate and antibiotics constitute the dominant self-medicated drugs compounding the situation in an era of antimicrobial resistance. Awareness campaigns on the dangers of self-medication will be timely.https://doi.org/10.1186/s12889-025-21380-9Self MedicationSelfcareSelf prescriptionNon-prescription medicationAntimicrobial resistance
spellingShingle Danladi Makeri
Priscilla Peter Dilli
Theophilus Pius
Naheem Adekilekun Tijani
Abdullateef Afolabi Opeyemi
Kadai Alhaji Lawan
Shango Patience Emmanuel Jakheng
Reagan Muhwezi
Ambrose Shabohurira
Ibe Michael Usman
Ezera Agwu
The nature of self-medication in Uganda: a systematic review and meta-analysis
BMC Public Health
Self Medication
Selfcare
Self prescription
Non-prescription medication
Antimicrobial resistance
title The nature of self-medication in Uganda: a systematic review and meta-analysis
title_full The nature of self-medication in Uganda: a systematic review and meta-analysis
title_fullStr The nature of self-medication in Uganda: a systematic review and meta-analysis
title_full_unstemmed The nature of self-medication in Uganda: a systematic review and meta-analysis
title_short The nature of self-medication in Uganda: a systematic review and meta-analysis
title_sort nature of self medication in uganda a systematic review and meta analysis
topic Self Medication
Selfcare
Self prescription
Non-prescription medication
Antimicrobial resistance
url https://doi.org/10.1186/s12889-025-21380-9
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