Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy

Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy

Inflammation and oxidative stress are involved in Proliferative Retinopathies (PR). Müller glial cells (MGCs) and microglia play pivotal roles in pathological neovascularization (NV) and neurodegeneration in PR. Nitro-fatty acids are important electrophilic signaling mediators with anti-inflammatory...

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Bibliographic Details
Main Authors: Vaglienti María Victoria, Paz María Constanza, Gutierrez Maria Victoria, Subirada Paula Virginia, Luna Jose, Bonacci Gustavo, Sánchez María Cecilia
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Redox Biology
Subjects:
Nitro-fatty acids
Retinal function
Proliferative retinopathies
Gliosis
IBA1+ retinal myeloid cells
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001478
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