Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report
Miescher’s cheilitis (MC) is a rare, idiopathic inflammatory condition marked by recurrent or persistent swelling of the lips and adjacent orofacial areas. This case study aims to explore the clinical presentation of Miescher’s cheilitis and evaluate the effectiveness of intralesional corticosteroid...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/61/2/299 |
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| author | Katarzyna Błochowiak Aya Kraiz Monika Bowszyc-Dmochowska Elżbieta Paszyńska Dorota Jenerowicz |
| author_facet | Katarzyna Błochowiak Aya Kraiz Monika Bowszyc-Dmochowska Elżbieta Paszyńska Dorota Jenerowicz |
| author_sort | Katarzyna Błochowiak |
| collection | DOAJ |
| description | Miescher’s cheilitis (MC) is a rare, idiopathic inflammatory condition marked by recurrent or persistent swelling of the lips and adjacent orofacial areas. This case study aims to explore the clinical presentation of Miescher’s cheilitis and evaluate the effectiveness of intralesional corticosteroid therapy as a treatment approach. A 58-year-old male presented with severe, persistent swelling of both the upper and lower lips, which had been ongoing for six months. The initial treatment with chloroquine was discontinued due to adverse effects and no efficacy. Subsequent treatment involved intralesional injections of triamcinolone acetonide, administered at concentrations of 10 mg/mL and 40 mg/mL. After a total of ten injection sessions, the patient experienced a nearly 70% reduction in lip swelling, with the therapeutic effect lasting for 9 months. Intralesional corticosteroid therapy proved to be an effective treatment for Miescher’s cheilitis, offering significant symptom relief and improvement in lip swelling when other treatments were ineffective or unsuitable. This case highlights the need for individualized treatment plans and underscores the importance of ongoing research to refine management strategies for this challenging condition. |
| format | Article |
| id | doaj-art-b4d573aa38b14a8896ae0b6f3473204f |
| institution | DOAJ |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-b4d573aa38b14a8896ae0b6f3473204f2025-08-20T02:44:46ZengMDPI AGMedicina1010-660X1648-91442025-02-0161229910.3390/medicina61020299Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case ReportKatarzyna Błochowiak0Aya Kraiz1Monika Bowszyc-Dmochowska2Elżbieta Paszyńska3Dorota Jenerowicz4Department of Oral Surgery, Periodontal Diseases and Oral Mucosal Diseases, Poznan University of Medical Sciences, 61-701 Poznan, PolandDepartment of Oral Surgery, Periodontal Diseases and Oral Mucosal Diseases, Poznan University of Medical Sciences, 61-701 Poznan, PolandDepartment of Dermatology, Poznan University of Medical Sciences, 61-701 Poznan, PolandDepartment of Integrated Dentistry, Community Dentistry Section, Poznan University of Medical Sciences, 61-701 Poznan, PolandDepartment of Dermatology, Poznan University of Medical Sciences, 61-701 Poznan, PolandMiescher’s cheilitis (MC) is a rare, idiopathic inflammatory condition marked by recurrent or persistent swelling of the lips and adjacent orofacial areas. This case study aims to explore the clinical presentation of Miescher’s cheilitis and evaluate the effectiveness of intralesional corticosteroid therapy as a treatment approach. A 58-year-old male presented with severe, persistent swelling of both the upper and lower lips, which had been ongoing for six months. The initial treatment with chloroquine was discontinued due to adverse effects and no efficacy. Subsequent treatment involved intralesional injections of triamcinolone acetonide, administered at concentrations of 10 mg/mL and 40 mg/mL. After a total of ten injection sessions, the patient experienced a nearly 70% reduction in lip swelling, with the therapeutic effect lasting for 9 months. Intralesional corticosteroid therapy proved to be an effective treatment for Miescher’s cheilitis, offering significant symptom relief and improvement in lip swelling when other treatments were ineffective or unsuitable. This case highlights the need for individualized treatment plans and underscores the importance of ongoing research to refine management strategies for this challenging condition.https://www.mdpi.com/1648-9144/61/2/299Miescher’s cheilitisgranulomatous cheilitisintralesional corticosteroidsorofacial granulomatosisMelkersson–Rosenthal syndromelip swelling |
| spellingShingle | Katarzyna Błochowiak Aya Kraiz Monika Bowszyc-Dmochowska Elżbieta Paszyńska Dorota Jenerowicz Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report Medicina Miescher’s cheilitis granulomatous cheilitis intralesional corticosteroids orofacial granulomatosis Melkersson–Rosenthal syndrome lip swelling |
| title | Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report |
| title_full | Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report |
| title_fullStr | Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report |
| title_full_unstemmed | Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report |
| title_short | Miescher’s Cheilitis as a Diagnostic and Therapeutic Challenge—A Case Report |
| title_sort | miescher s cheilitis as a diagnostic and therapeutic challenge a case report |
| topic | Miescher’s cheilitis granulomatous cheilitis intralesional corticosteroids orofacial granulomatosis Melkersson–Rosenthal syndrome lip swelling |
| url | https://www.mdpi.com/1648-9144/61/2/299 |
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