Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers

Heart failure (HF) is a common condition and one of the main morbidity and mortality factors in elderly patients. The incidence of HF progressively increases with age, reaching >10% in those aged 70 years or over. In the elderly population, both the diagnosis and the management of HF prove challe...

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Main Authors: Paulina Nadziakiewicz, Wioletta Szczurek-Wasilewicz, Bożena Szyguła-Jurkiewicz
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
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Online Access:https://www.mdpi.com/1424-8247/18/1/32
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author Paulina Nadziakiewicz
Wioletta Szczurek-Wasilewicz
Bożena Szyguła-Jurkiewicz
author_facet Paulina Nadziakiewicz
Wioletta Szczurek-Wasilewicz
Bożena Szyguła-Jurkiewicz
author_sort Paulina Nadziakiewicz
collection DOAJ
description Heart failure (HF) is a common condition and one of the main morbidity and mortality factors in elderly patients. The incidence of HF progressively increases with age, reaching >10% in those aged 70 years or over. In the elderly population, both the diagnosis and the management of HF prove challenging, often requiring specialized care and a multidisciplinary approach. In seniors, atypical presentation of HF is much more common than in younger patients; thus, a holistic assessment with biomarkers related to HF allows for early diagnosis and accurate risk stratification in this group of patients. This article reviews the clinical and diagnostic differences in elderly patients with HF, highlighting the presence of comorbidities, frailty, cognitive impairment, and polypharmacy, as well as discussing potential biomarkers that may have clinical application in this population.
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institution Kabale University
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publishDate 2024-12-01
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series Pharmaceuticals
spelling doaj-art-b4d07f3f5b4e433aa3f932bf205c2dcc2025-01-24T13:45:05ZengMDPI AGPharmaceuticals1424-82472024-12-011813210.3390/ph18010032Heart Failure in Elderly Patients: Medical Management, Therapies and BiomarkersPaulina Nadziakiewicz0Wioletta Szczurek-Wasilewicz1Bożena Szyguła-Jurkiewicz2Student’s Scientific Society, 3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandDepartment of Pharmacology, Faculty of Medicine, University of Opole, 45-052 Opole, Poland3rd Department of Cardiology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, PolandHeart failure (HF) is a common condition and one of the main morbidity and mortality factors in elderly patients. The incidence of HF progressively increases with age, reaching >10% in those aged 70 years or over. In the elderly population, both the diagnosis and the management of HF prove challenging, often requiring specialized care and a multidisciplinary approach. In seniors, atypical presentation of HF is much more common than in younger patients; thus, a holistic assessment with biomarkers related to HF allows for early diagnosis and accurate risk stratification in this group of patients. This article reviews the clinical and diagnostic differences in elderly patients with HF, highlighting the presence of comorbidities, frailty, cognitive impairment, and polypharmacy, as well as discussing potential biomarkers that may have clinical application in this population.https://www.mdpi.com/1424-8247/18/1/32heart failurebiomarkerselderly patientspharmacological treatmentcomorbidities
spellingShingle Paulina Nadziakiewicz
Wioletta Szczurek-Wasilewicz
Bożena Szyguła-Jurkiewicz
Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
Pharmaceuticals
heart failure
biomarkers
elderly patients
pharmacological treatment
comorbidities
title Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
title_full Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
title_fullStr Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
title_full_unstemmed Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
title_short Heart Failure in Elderly Patients: Medical Management, Therapies and Biomarkers
title_sort heart failure in elderly patients medical management therapies and biomarkers
topic heart failure
biomarkers
elderly patients
pharmacological treatment
comorbidities
url https://www.mdpi.com/1424-8247/18/1/32
work_keys_str_mv AT paulinanadziakiewicz heartfailureinelderlypatientsmedicalmanagementtherapiesandbiomarkers
AT wiolettaszczurekwasilewicz heartfailureinelderlypatientsmedicalmanagementtherapiesandbiomarkers
AT bozenaszygułajurkiewicz heartfailureinelderlypatientsmedicalmanagementtherapiesandbiomarkers