A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis
Since treatment of active disease remains the priority for tuberculosis control, donors and governments need to be convinced that investing resources in chemoprophylaxis provides health benefits and is good value for money. The limited evidence of cost effectiveness has often been presented in a fra...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/130976 |
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| author | Shraddha Chavan David Newlands Cairns Smith |
| author_facet | Shraddha Chavan David Newlands Cairns Smith |
| author_sort | Shraddha Chavan |
| collection | DOAJ |
| description | Since treatment of active disease remains the priority for tuberculosis control, donors and governments need to be convinced that investing resources in chemoprophylaxis provides health benefits and is good value for money. The limited evidence of cost effectiveness has often been presented in a fragmentary and inconsistent fashion. Objective. This review is aimed at critically reviewing the evidence of cost effectiveness of chemoprophylaxis against tuberculosis, identifying the important knowledge gaps and the current issues which confront policy makers. Methods. A systematic search on economic evaluations for chemoprophylaxis against tuberculosis was carried out, and the selected studies were checked for quality assessment against a standard checklist. Results. The review provides evidence of the cost effectiveness of chemoprophylaxis for all age groups which suggests that current policy should be amended to include a focus on older adults. Seven of the eight selected studies were undertaken wholly in high income countries but there are considerable doubts about the transferability of the findings of the selected studies to low and middle income countries which have the greatest incidence of latent tuberculosis infection. Conclusion. There is a pressing need to expand the evidence base to low and middle income countries where the vast majority of sufferers from tuberculosis live. |
| format | Article |
| id | doaj-art-b4a4d10cbc084a0bb1427adf589e82a5 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-b4a4d10cbc084a0bb1427adf589e82a52025-02-03T01:11:37ZengWileyJournal of Tropical Medicine1687-96861687-96942011-01-01201110.1155/2011/130976130976A Systematic Review of Economic Evaluations of Chemoprophylaxis for TuberculosisShraddha Chavan0David Newlands1Cairns Smith2Population Health Section, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen AB24 3fx, UKEconomics Department, Business School, University of Aberdeen, Aberdeen AB24 3fx, UKPopulation Health Section, Institute of Applied Health Sciences, University of Aberdeen, Aberdeen AB24 3fx, UKSince treatment of active disease remains the priority for tuberculosis control, donors and governments need to be convinced that investing resources in chemoprophylaxis provides health benefits and is good value for money. The limited evidence of cost effectiveness has often been presented in a fragmentary and inconsistent fashion. Objective. This review is aimed at critically reviewing the evidence of cost effectiveness of chemoprophylaxis against tuberculosis, identifying the important knowledge gaps and the current issues which confront policy makers. Methods. A systematic search on economic evaluations for chemoprophylaxis against tuberculosis was carried out, and the selected studies were checked for quality assessment against a standard checklist. Results. The review provides evidence of the cost effectiveness of chemoprophylaxis for all age groups which suggests that current policy should be amended to include a focus on older adults. Seven of the eight selected studies were undertaken wholly in high income countries but there are considerable doubts about the transferability of the findings of the selected studies to low and middle income countries which have the greatest incidence of latent tuberculosis infection. Conclusion. There is a pressing need to expand the evidence base to low and middle income countries where the vast majority of sufferers from tuberculosis live.http://dx.doi.org/10.1155/2011/130976 |
| spellingShingle | Shraddha Chavan David Newlands Cairns Smith A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis Journal of Tropical Medicine |
| title | A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis |
| title_full | A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis |
| title_fullStr | A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis |
| title_full_unstemmed | A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis |
| title_short | A Systematic Review of Economic Evaluations of Chemoprophylaxis for Tuberculosis |
| title_sort | systematic review of economic evaluations of chemoprophylaxis for tuberculosis |
| url | http://dx.doi.org/10.1155/2011/130976 |
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