Exercise Interventions in Children with Cancer: A Review

The purpose of this review is to summarize literature that describes the impact of exercise on health and physical function among children during and after treatment for cancer. Relevant studies were identified by entering the following search terms into Pubmed: aerobic training; resistance training...

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Main Authors: Tseng-Tien Huang, Kirsten K. Ness
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2011/461512
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author Tseng-Tien Huang
Kirsten K. Ness
author_facet Tseng-Tien Huang
Kirsten K. Ness
author_sort Tseng-Tien Huang
collection DOAJ
description The purpose of this review is to summarize literature that describes the impact of exercise on health and physical function among children during and after treatment for cancer. Relevant studies were identified by entering the following search terms into Pubmed: aerobic training; resistance training; stretching; pediatric; children; AND cancer. Reference lists in retrieved manuscripts were also reviewed to identify additional trials. We include fifteen intervention trials published between 1993 and 2011 that included children younger than age 21 years with cancer diagnoses. Nine included children with an acute lymphoblastic leukemia (ALL) diagnosis, and six children with mixed cancer diagnoses. Generally, interventions tested were either in-hospital supervised exercise training or home based programs designed to promote physical activity. Early evidence from small studies indicates that the effects of exercise include increased cardiopulmonary fitness, improved muscle strength and flexibility, reduced fatigue and improved physical function. Generalizations to the entire childhood cancer and childhood cancer survivor populations are difficult as most of the work has been done in children during treatment for and among survivors of ALL. Additional randomized studies are needed to confirm these benefits in larger populations of children with ALL, and in populations with cancer diagnoses other than ALL.
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spelling doaj-art-b49a94b90cf34770b5d55de990c03e0c2025-02-03T01:10:59ZengWileyInternational Journal of Pediatrics1687-97401687-97592011-01-01201110.1155/2011/461512461512Exercise Interventions in Children with Cancer: A ReviewTseng-Tien Huang0Kirsten K. Ness1Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USADepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN 38105, USAThe purpose of this review is to summarize literature that describes the impact of exercise on health and physical function among children during and after treatment for cancer. Relevant studies were identified by entering the following search terms into Pubmed: aerobic training; resistance training; stretching; pediatric; children; AND cancer. Reference lists in retrieved manuscripts were also reviewed to identify additional trials. We include fifteen intervention trials published between 1993 and 2011 that included children younger than age 21 years with cancer diagnoses. Nine included children with an acute lymphoblastic leukemia (ALL) diagnosis, and six children with mixed cancer diagnoses. Generally, interventions tested were either in-hospital supervised exercise training or home based programs designed to promote physical activity. Early evidence from small studies indicates that the effects of exercise include increased cardiopulmonary fitness, improved muscle strength and flexibility, reduced fatigue and improved physical function. Generalizations to the entire childhood cancer and childhood cancer survivor populations are difficult as most of the work has been done in children during treatment for and among survivors of ALL. Additional randomized studies are needed to confirm these benefits in larger populations of children with ALL, and in populations with cancer diagnoses other than ALL.http://dx.doi.org/10.1155/2011/461512
spellingShingle Tseng-Tien Huang
Kirsten K. Ness
Exercise Interventions in Children with Cancer: A Review
International Journal of Pediatrics
title Exercise Interventions in Children with Cancer: A Review
title_full Exercise Interventions in Children with Cancer: A Review
title_fullStr Exercise Interventions in Children with Cancer: A Review
title_full_unstemmed Exercise Interventions in Children with Cancer: A Review
title_short Exercise Interventions in Children with Cancer: A Review
title_sort exercise interventions in children with cancer a review
url http://dx.doi.org/10.1155/2011/461512
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