Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity

Abstract In the digital age, privacy preservation is of paramount importance while processing health-related sensitive information. This paper explores the integration of Federated Learning (FL) and Differential Privacy (DP) for breast cancer detection, leveraging FL’s decentralized architecture to...

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Main Authors: Shubhi Shukla, Suraksha Rajkumar, Aditi Sinha, Mohamed Esha, Konguvel Elango, Vidhya Sampath
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-95858-2
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author Shubhi Shukla
Suraksha Rajkumar
Aditi Sinha
Mohamed Esha
Konguvel Elango
Vidhya Sampath
author_facet Shubhi Shukla
Suraksha Rajkumar
Aditi Sinha
Mohamed Esha
Konguvel Elango
Vidhya Sampath
author_sort Shubhi Shukla
collection DOAJ
description Abstract In the digital age, privacy preservation is of paramount importance while processing health-related sensitive information. This paper explores the integration of Federated Learning (FL) and Differential Privacy (DP) for breast cancer detection, leveraging FL’s decentralized architecture to enable collaborative model training across healthcare organizations without exposing raw patient data. To enhance privacy, DP injects statistical noise into the updates made by the model. This mitigates adversarial attacks and prevents data leakage. The proposed work uses the Breast Cancer Wisconsin Diagnostic dataset to address critical challenges such as data heterogeneity, privacy-accuracy trade-offs, and computational overhead. From the experimental results, FL combined with DP achieves 96.1% accuracy with a privacy budget of ε = 1.9, ensuring strong privacy preservation with minimal performance trade-offs. In comparison, the traditional non-FL model achieved 96.0% accuracy, but at the cost of requiring centralized data storage, which poses significant privacy risks. These findings validate the feasibility of privacy-preserving artificial intelligence models in real-world clinical applications, effectively balancing data protection with reliable medical predictions.
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spelling doaj-art-b496afb32c2048338fb04db39dbef4fe2025-08-20T02:27:52ZengNature PortfolioScientific Reports2045-23222025-04-0115113310.1038/s41598-025-95858-2Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrityShubhi Shukla0Suraksha Rajkumar1Aditi Sinha2Mohamed Esha3Konguvel Elango4Vidhya Sampath5School of Electrical Engineering, Vellore Institute of TechnologySchool of Electronics Engineering, Vellore Institute of TechnologySchool of Electronics Engineering, Vellore Institute of TechnologySchool of Mechanical Engineering, Vellore Institute of TechnologySchool of Electronics Engineering, Vellore Institute of TechnologySchool of Electronics Engineering, Vellore Institute of TechnologyAbstract In the digital age, privacy preservation is of paramount importance while processing health-related sensitive information. This paper explores the integration of Federated Learning (FL) and Differential Privacy (DP) for breast cancer detection, leveraging FL’s decentralized architecture to enable collaborative model training across healthcare organizations without exposing raw patient data. To enhance privacy, DP injects statistical noise into the updates made by the model. This mitigates adversarial attacks and prevents data leakage. The proposed work uses the Breast Cancer Wisconsin Diagnostic dataset to address critical challenges such as data heterogeneity, privacy-accuracy trade-offs, and computational overhead. From the experimental results, FL combined with DP achieves 96.1% accuracy with a privacy budget of ε = 1.9, ensuring strong privacy preservation with minimal performance trade-offs. In comparison, the traditional non-FL model achieved 96.0% accuracy, but at the cost of requiring centralized data storage, which poses significant privacy risks. These findings validate the feasibility of privacy-preserving artificial intelligence models in real-world clinical applications, effectively balancing data protection with reliable medical predictions.https://doi.org/10.1038/s41598-025-95858-2Federated learningData securityPrivacy preservationHealthcareDecentralized machine learningDifferential privacy
spellingShingle Shubhi Shukla
Suraksha Rajkumar
Aditi Sinha
Mohamed Esha
Konguvel Elango
Vidhya Sampath
Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
Scientific Reports
Federated learning
Data security
Privacy preservation
Healthcare
Decentralized machine learning
Differential privacy
title Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
title_full Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
title_fullStr Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
title_full_unstemmed Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
title_short Federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
title_sort federated learning with differential privacy for breast cancer diagnosis enabling secure data sharing and model integrity
topic Federated learning
Data security
Privacy preservation
Healthcare
Decentralized machine learning
Differential privacy
url https://doi.org/10.1038/s41598-025-95858-2
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