Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice
In this study, the hepatoprotective and hypolipidemic effects of high-polydextrose snack food on Swiss albino mice were investigated. The mice were randomly divided into three groups: control diet, high-fat diet, and high-fat and fiber diet groups. Addition of high-polydextrose snack to the high-fat...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2020/5104231 |
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| author | Jin Han Yang Thi Thu Tra Tran Van Viet Man Le |
| author_facet | Jin Han Yang Thi Thu Tra Tran Van Viet Man Le |
| author_sort | Jin Han Yang |
| collection | DOAJ |
| description | In this study, the hepatoprotective and hypolipidemic effects of high-polydextrose snack food on Swiss albino mice were investigated. The mice were randomly divided into three groups: control diet, high-fat diet, and high-fat and fiber diet groups. Addition of high-polydextrose snack to the high-fat diet resulted in significant reduction in the liver weight, the accumulation of lipid droplets in liver, and the liver damage of hyperlipidemic mice in comparison with the high-fat diet. The high-polydextrose snack also decreased the content of total triglyceride, cholesterol, and low-density lipoprotein cholesterol as well as the alanine aminotransferase and aspartate aminotransferase activities in the mice serum. In addition, the high-polydextrose snack significantly increased the high-density lipoprotein cholesterol content of the hyperlipidemic mice. Consequently, use of high-polydextrose snack generated hepatoprotective and hypolipidemic effects on hyperlipidemic mice. |
| format | Article |
| id | doaj-art-b4956a8e65374278997fc1c18ccdd2d7 |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-b4956a8e65374278997fc1c18ccdd2d72025-02-03T01:04:30ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322020-01-01202010.1155/2020/51042315104231Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino MiceJin Han Yang0Thi Thu Tra Tran1Van Viet Man Le2Department of Food Technology, Ho Chi Minh City University of Technology Vietnam National University-Ho Chi Minh City (VNU-HCM) 268 Ly Thuong Kiet, District 10, Ho Chi Minh, VietnamDepartment of Food Technology, Ho Chi Minh City University of Technology Vietnam National University-Ho Chi Minh City (VNU-HCM) 268 Ly Thuong Kiet, District 10, Ho Chi Minh, VietnamDepartment of Food Technology, Ho Chi Minh City University of Technology Vietnam National University-Ho Chi Minh City (VNU-HCM) 268 Ly Thuong Kiet, District 10, Ho Chi Minh, VietnamIn this study, the hepatoprotective and hypolipidemic effects of high-polydextrose snack food on Swiss albino mice were investigated. The mice were randomly divided into three groups: control diet, high-fat diet, and high-fat and fiber diet groups. Addition of high-polydextrose snack to the high-fat diet resulted in significant reduction in the liver weight, the accumulation of lipid droplets in liver, and the liver damage of hyperlipidemic mice in comparison with the high-fat diet. The high-polydextrose snack also decreased the content of total triglyceride, cholesterol, and low-density lipoprotein cholesterol as well as the alanine aminotransferase and aspartate aminotransferase activities in the mice serum. In addition, the high-polydextrose snack significantly increased the high-density lipoprotein cholesterol content of the hyperlipidemic mice. Consequently, use of high-polydextrose snack generated hepatoprotective and hypolipidemic effects on hyperlipidemic mice.http://dx.doi.org/10.1155/2020/5104231 |
| spellingShingle | Jin Han Yang Thi Thu Tra Tran Van Viet Man Le Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice Journal of Nutrition and Metabolism |
| title | Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice |
| title_full | Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice |
| title_fullStr | Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice |
| title_full_unstemmed | Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice |
| title_short | Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice |
| title_sort | hypolipidemic and hepatoprotective effects of high polydextrose snack food on swiss albino mice |
| url | http://dx.doi.org/10.1155/2020/5104231 |
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