Leptin In Malign Pleural Efusions: May Be A New Marker?
Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and malignant pleural effusions (n=20), and health...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2011-12-01
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| Series: | Ankara Üniversitesi Tıp Fakültesi Mecmuas |
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http://ankaratipfakultesimecmuasi.net/archives/archive-detail/article-preview/leptin-n-malign-pleural-efusions-may-be-a-new-mark/18582
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| author | Serap Duru Zeynep Sönmez Yasemin Saygıdeger Alper Dilli Günnur Dikmen Özlem Sever Sadık Ardıç |
| author_facet | Serap Duru Zeynep Sönmez Yasemin Saygıdeger Alper Dilli Günnur Dikmen Özlem Sever Sadık Ardıç |
| author_sort | Serap Duru |
| collection | DOAJ |
| description | Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and malignant pleural effusions (n=20), and healthy control group (n=20) were included in this cross-sectional study. The age and body mass index (BMI) were comparative between study groups. The serum leptin levels in all subjects and pleural effu-sions leptin level in patients with pleural effusion were determined. Leptin levels were compared in terms of study groups and gender of subjects.Results: The leptin levels in serum and pleural effusions in group with malignant pleural effusion were significantly higher than both the non-malignant effusion and control groups (p<0.001). While there was no statistically significant difference between male and female patients in terms of pleural effusions leptin levels (p=0.097), serum leptin level of the female patients was significantly higher than the male patients (p<0.001).Conclusion: Increased serum and pleural effusions leptin levels in malignant pleural effusions shows that leptin is a useful new marker. |
| format | Article |
| id | doaj-art-b48030f3d3ad4f89806c0ee1b78af443 |
| institution | Kabale University |
| issn | 1307-5608 1307-5608 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Ankara Üniversitesi Tıp Fakültesi Mecmuas |
| spelling | doaj-art-b48030f3d3ad4f89806c0ee1b78af4432025-08-20T03:39:22ZengGalenos Publishing HouseAnkara Üniversitesi Tıp Fakültesi Mecmuas1307-56081307-56082011-12-0164312713110.1501/Tipfak_000000079613049054Leptin In Malign Pleural Efusions: May Be A New Marker?Serap Duru0Zeynep Sönmez1Yasemin Saygıdeger2Alper Dilli3Günnur Dikmen4Özlem Sever5Sadık Ardıç6 Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, Ankara Afyon Göğüs Hastalıkları Hastanesi, Afyon Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Radyoloji Kliniği, Ankara Hacettepe Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Göğüs Hastalıkları Kliniği, Ankara Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and malignant pleural effusions (n=20), and healthy control group (n=20) were included in this cross-sectional study. The age and body mass index (BMI) were comparative between study groups. The serum leptin levels in all subjects and pleural effu-sions leptin level in patients with pleural effusion were determined. Leptin levels were compared in terms of study groups and gender of subjects.Results: The leptin levels in serum and pleural effusions in group with malignant pleural effusion were significantly higher than both the non-malignant effusion and control groups (p<0.001). While there was no statistically significant difference between male and female patients in terms of pleural effusions leptin levels (p=0.097), serum leptin level of the female patients was significantly higher than the male patients (p<0.001).Conclusion: Increased serum and pleural effusions leptin levels in malignant pleural effusions shows that leptin is a useful new marker. http://ankaratipfakultesimecmuasi.net/archives/archive-detail/article-preview/leptin-n-malign-pleural-efusions-may-be-a-new-mark/18582 Leptinmalignancypleural effusion |
| spellingShingle | Serap Duru Zeynep Sönmez Yasemin Saygıdeger Alper Dilli Günnur Dikmen Özlem Sever Sadık Ardıç Leptin In Malign Pleural Efusions: May Be A New Marker? Ankara Üniversitesi Tıp Fakültesi Mecmuas Leptin malignancy pleural effusion |
| title | Leptin In Malign Pleural Efusions: May Be A New Marker? |
| title_full | Leptin In Malign Pleural Efusions: May Be A New Marker? |
| title_fullStr | Leptin In Malign Pleural Efusions: May Be A New Marker? |
| title_full_unstemmed | Leptin In Malign Pleural Efusions: May Be A New Marker? |
| title_short | Leptin In Malign Pleural Efusions: May Be A New Marker? |
| title_sort | leptin in malign pleural efusions may be a new marker |
| topic | Leptin malignancy pleural effusion |
| url |
http://ankaratipfakultesimecmuasi.net/archives/archive-detail/article-preview/leptin-n-malign-pleural-efusions-may-be-a-new-mark/18582
|
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