Leptin In Malign Pleural Efusions: May Be A New Marker?
Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and malignant pleural effusions (n=20), and health...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2011-12-01
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| Series: | Ankara Üniversitesi Tıp Fakültesi Mecmuas |
| Subjects: | |
| Online Access: |
http://ankaratipfakultesimecmuasi.net/archives/archive-detail/article-preview/leptin-n-malign-pleural-efusions-may-be-a-new-mark/18582
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| Summary: | Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and malignant pleural effusions (n=20), and healthy control group (n=20) were included in this cross-sectional study. The age and body mass index (BMI) were comparative between study groups. The serum leptin levels in all subjects and pleural effu-sions leptin level in patients with pleural effusion were determined. Leptin levels were compared in terms of study groups and gender of subjects.Results: The leptin levels in serum and pleural effusions in group with malignant pleural effusion were significantly higher than both the non-malignant effusion and control groups (p<0.001). While there was no statistically significant difference between male and female patients in terms of pleural effusions leptin levels (p=0.097), serum leptin level of the female patients was significantly higher than the male patients (p<0.001).Conclusion: Increased serum and pleural effusions leptin levels in malignant pleural effusions shows that leptin is a useful new marker. |
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| ISSN: | 1307-5608 1307-5608 |