Anti-PD1-/PDL1-induced chronic intestinal pseudo-obstruction: three cases treated with vedolizumab after corticosteroid failure with mixed results

Abstract Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers. Increased use of ICI has led to the onset of new adverse events. Neurological immune-related adverse events are rare, heterogenous, and potentially life-threatening. Chronic...

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Main Authors: Morgan Zenatri, Michael Collins, Tifanie Alberto, Antonio Farina, Sophie Collardeau-Frachon, Mélanie Saint-Jean, François Bocquet, Frederic Dumont, Jérôme Honnorat, Bastien Joubert, Judith Raimbourg
Format: Article
Language:English
Published: Springer 2025-01-01
Series:Cancer Immunology, Immunotherapy
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Online Access:https://doi.org/10.1007/s00262-024-03901-4
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