Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats
BACKGROUND: Sudden, severe airway injury has been associated with an acute, and at times persisting, airway hyper-responsiveness with clinical features of asthma, termed reactive airways dysfunction syndrome (RADS). An attempt was made to develop a rat model of RADS by exposing inbred Fischer rats t...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1998-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/1998/157193 |
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| _version_ | 1832560755764887552 |
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| author | AP Ariel HG Furlott KR Chapman AS Slutsky P Webster N Zamel SM Tarlo |
| author_facet | AP Ariel HG Furlott KR Chapman AS Slutsky P Webster N Zamel SM Tarlo |
| author_sort | AP Ariel |
| collection | DOAJ |
| description | BACKGROUND: Sudden, severe airway injury has been associated with an acute, and at times persisting, airway hyper-responsiveness with clinical features of asthma, termed reactive airways dysfunction syndrome (RADS). An attempt was made to develop a rat model of RADS by exposing inbred Fischer rats to inhaled 8 N acetic acid for 2 mins (13 N inhalation was lethal). |
| format | Article |
| id | doaj-art-b41072ec18a1445d8e7301611768ec18 |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 1998-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-b41072ec18a1445d8e7301611768ec182025-02-03T01:26:52ZengWileyCanadian Respiratory Journal1198-22411998-01-015534935410.1155/1998/157193Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer RatsAP Ariel0HG Furlott1KR Chapman2AS Slutsky3P Webster4N Zamel5SM Tarlo6Department of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaDepartment of Medicine, University of Toronto, Toronto, Ontario, CanadaBACKGROUND: Sudden, severe airway injury has been associated with an acute, and at times persisting, airway hyper-responsiveness with clinical features of asthma, termed reactive airways dysfunction syndrome (RADS). An attempt was made to develop a rat model of RADS by exposing inbred Fischer rats to inhaled 8 N acetic acid for 2 mins (13 N inhalation was lethal).http://dx.doi.org/10.1155/1998/157193 |
| spellingShingle | AP Ariel HG Furlott KR Chapman AS Slutsky P Webster N Zamel SM Tarlo Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats Canadian Respiratory Journal |
| title | Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats |
| title_full | Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats |
| title_fullStr | Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats |
| title_full_unstemmed | Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats |
| title_short | Effect of High Dose Inhaled Acetic Acid on Airway Responsiveness in Fischer Rats |
| title_sort | effect of high dose inhaled acetic acid on airway responsiveness in fischer rats |
| url | http://dx.doi.org/10.1155/1998/157193 |
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