Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report

Verrucous carcinoma of the foot often affects deep structures such as tendons, muscles, or bones. A 74-year-old man presented with a foot lesion that had been diagnosed as a skin infection 7 years earlier. He was treated with multiple excisions and superficial biopsies associated with antibiotic the...

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Main Authors: C. Pempinello, A. Bova, R. Pempinello, R. Luise, G. Iannaci
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2013/135307
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author C. Pempinello
A. Bova
R. Pempinello
R. Luise
G. Iannaci
author_facet C. Pempinello
A. Bova
R. Pempinello
R. Luise
G. Iannaci
author_sort C. Pempinello
collection DOAJ
description Verrucous carcinoma of the foot often affects deep structures such as tendons, muscles, or bones. A 74-year-old man presented with a foot lesion that had been diagnosed as a skin infection 7 years earlier. He was treated with multiple excisions and superficial biopsies associated with antibiotic therapy without success. In our department he underwent an aggressive and accurate debridement with marginal excision harvesting multiple biopsies. Pathological evaluation of tissue at the time of operation confirmed the diagnosis of verrucous carcinoma of the foot. Therefore, the patient underwent an amputation below knee, and there were no postoperative complications; the patient was able to walk with the aid of a prosthesis with no signs of recurrence. The lesion follows a chronic course evolving from a discrete focal lesion to a large fungating deeply penetrating mass often compromised by local infection. The slow growth and confusing early-stage appearances can lead to delays in diagnosis of 8 to 15 years causing the extracutaneous involvement that requires a leg amputation. Many patients are initially treated with many topical medications without success, and most tumors have been treated as recalcitrant warts or corns for some time, whereas the basic approach is surgical.
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publishDate 2013-01-01
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series Case Reports in Oncological Medicine
spelling doaj-art-b3f4e90abdfb433ab09287da469d92622025-02-03T06:45:57ZengWileyCase Reports in Oncological Medicine2090-67062090-67142013-01-01201310.1155/2013/135307135307Verrucous Carcinoma of the Foot with Bone Invasion: A Case ReportC. Pempinello0A. Bova1R. Pempinello2R. Luise3G. Iannaci4Department of Orthopaedic and Traumatology, S. Gennaro Hospital, Via San Gennaro dei Poveri, 25-80125 Napoli, ItalyDepartment of Orthopaedic and Traumatology, S. Gennaro Hospital, Via San Gennaro dei Poveri, 25-80125 Napoli, ItalyDepartment of Infectious Diseases, Cotugno Hospital, Via G. Quagliariello, 54-80131 Napoli, ItalyDepartment of Pathology, Incurabili Hospital, Via Maria Longo, 50-80138 Napoli, ItalyDepartment of Pathology, Incurabili Hospital, Via Maria Longo, 50-80138 Napoli, ItalyVerrucous carcinoma of the foot often affects deep structures such as tendons, muscles, or bones. A 74-year-old man presented with a foot lesion that had been diagnosed as a skin infection 7 years earlier. He was treated with multiple excisions and superficial biopsies associated with antibiotic therapy without success. In our department he underwent an aggressive and accurate debridement with marginal excision harvesting multiple biopsies. Pathological evaluation of tissue at the time of operation confirmed the diagnosis of verrucous carcinoma of the foot. Therefore, the patient underwent an amputation below knee, and there were no postoperative complications; the patient was able to walk with the aid of a prosthesis with no signs of recurrence. The lesion follows a chronic course evolving from a discrete focal lesion to a large fungating deeply penetrating mass often compromised by local infection. The slow growth and confusing early-stage appearances can lead to delays in diagnosis of 8 to 15 years causing the extracutaneous involvement that requires a leg amputation. Many patients are initially treated with many topical medications without success, and most tumors have been treated as recalcitrant warts or corns for some time, whereas the basic approach is surgical.http://dx.doi.org/10.1155/2013/135307
spellingShingle C. Pempinello
A. Bova
R. Pempinello
R. Luise
G. Iannaci
Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
Case Reports in Oncological Medicine
title Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
title_full Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
title_fullStr Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
title_full_unstemmed Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
title_short Verrucous Carcinoma of the Foot with Bone Invasion: A Case Report
title_sort verrucous carcinoma of the foot with bone invasion a case report
url http://dx.doi.org/10.1155/2013/135307
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