Robust substrate profiling method reveals striking differences in specificities of serum and lung fluid proteases
Proteases are candidate biomarkers and therapeutic targets for many diseases. Sensitive and robust techniques are needed to quantify proteolytic activities within the complex biological milieu. We hypothesized that a combinatorial protease substrate library could be used effectively to identify simi...
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| Main Authors: | Douglas S. Watson, Kalyani Jambunathan, David S. Askew, Krishna Kodukula, Amit K. Galande |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2011-08-01
|
| Series: | BioTechniques |
| Subjects: | |
| Online Access: | https://www.future-science.com/doi/10.2144/000113717 |
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