CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype

CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype

Background Platinum resistance is a major challenge in the clinical treatment of advanced ovarian cancer (OC). Accumulating evidence shows that the tumor-promotive M2 macrophage is linked to the limiting chemotherapy efficacy of multiple malignancies including OC. Circular RNAs (circRNAs) are a nove...

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Main Authors: Jingjing Zhao, Yue Li, Yan Tang, Jian-Chuan Xia, Yue Huang, Mian He, Weijing Zhang, Libing Song, Han Li, Fan Luo, Xingyu Jiang, Tong Xiang, Qiuzhong Pan, Liming Cai, Desheng Weng, Yuhu Dai, Fengze Sun, Chaopin Yang, Jieying Yang, Yulong Han, Yanna Zhang
Format: Article
Language:English
Published: BMJ Publishing Group 2022-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/3/e004029.full
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