Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities
Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of multiple inflammatory genes, which then play a protective role against infection. However, aberrant activation of TLR signaling has a significant...
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Main Authors: | Jiankun Zhu, Chandra Mohan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2010/781235 |
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