A computational assessment of alkaloids targeting the plant homeodomain in pygopus2: inhibitory potential and drug-like properties
<p>Pygopus2 (Pygo2) is a component of the Wnt signaling pathway, crucial for β-catenin-mediated transcription during normal development. Overexpression of Pygo2 has been linked to various human cancers, including lung, colon, and brain cancers. The plant homeodomain (PHD) finger in Pygo2 inter...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academy Publishing Center
2024-09-01
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| Series: | Advances in Medical, Pharmaceutical and Dental Research |
| Subjects: | |
| Online Access: | http://apc.aast.edu/ojs/index.php/AMPDR/article/view/923 |
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