Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
Second cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myelom...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2013/417353 |
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| _version_ | 1832561311813206016 |
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| author | Giuseppe Mele Marilena Greco Maria Rosaria Coppi Giacomo Loseto Angela Melpignano Salvatore Mauro Gianni Quarta |
| author_facet | Giuseppe Mele Marilena Greco Maria Rosaria Coppi Giacomo Loseto Angela Melpignano Salvatore Mauro Gianni Quarta |
| author_sort | Giuseppe Mele |
| collection | DOAJ |
| description | Second cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myeloma (MM). Does asymptomatic clonal T-cell large granular lymphocytic proliferation, in our experience, represent either a secondary cancer after auto-SCT or clonal T cell aberration or derive from expansion of coexisting undetected small-sized clone of T cells? |
| format | Article |
| id | doaj-art-b3ab333ff5054eb5a6a7cc8e8952004a |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-b3ab333ff5054eb5a6a7cc8e8952004a2025-02-03T01:25:28ZengWileyCase Reports in Hematology2090-65602090-65792013-01-01201310.1155/2013/417353417353Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?Giuseppe Mele0Marilena Greco1Maria Rosaria Coppi2Giacomo Loseto3Angela Melpignano4Salvatore Mauro5Gianni Quarta6Haematology Division and BMT Unit, Antonio Perrino Hospital, 72100 Brindisi, ItalyLaboratory of Genetic, Vito Fazzi Hospital, 73100 Lecce, ItalyHaematology Division and BMT Unit, Antonio Perrino Hospital, 72100 Brindisi, ItalyHaematology Division and BMT Unit, Antonio Perrino Hospital, 72100 Brindisi, ItalyHaematology Division and BMT Unit, Antonio Perrino Hospital, 72100 Brindisi, ItalyLaboratory of Genetic, Vito Fazzi Hospital, 73100 Lecce, ItalyHaematology Division and BMT Unit, Antonio Perrino Hospital, 72100 Brindisi, ItalySecond cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myeloma (MM). Does asymptomatic clonal T-cell large granular lymphocytic proliferation, in our experience, represent either a secondary cancer after auto-SCT or clonal T cell aberration or derive from expansion of coexisting undetected small-sized clone of T cells?http://dx.doi.org/10.1155/2013/417353 |
| spellingShingle | Giuseppe Mele Marilena Greco Maria Rosaria Coppi Giacomo Loseto Angela Melpignano Salvatore Mauro Gianni Quarta Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? Case Reports in Hematology |
| title | Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? |
| title_full | Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? |
| title_fullStr | Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? |
| title_full_unstemmed | Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? |
| title_short | Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? |
| title_sort | small sized clone of t cells in multiple myeloma patient after auto sct t lgl leukemia type or clonal t cell aberration |
| url | http://dx.doi.org/10.1155/2013/417353 |
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