Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Skin regeneration is a vexing problem in the field of regenerative medicine. A bioactive molecule-based strategy has been frequently used in skin wound healing in recent years. Bioactive molecules are practical tools for regulating cellular processes and have been applied to control cellular differe...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2019/6789823 |
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| _version_ | 1832552038312968192 |
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| author | Deyun Chen Qian Hou Lingzhi Zhong Yali Zhao Meirong Li Xiaobing Fu |
| author_facet | Deyun Chen Qian Hou Lingzhi Zhong Yali Zhao Meirong Li Xiaobing Fu |
| author_sort | Deyun Chen |
| collection | DOAJ |
| description | Skin regeneration is a vexing problem in the field of regenerative medicine. A bioactive molecule-based strategy has been frequently used in skin wound healing in recent years. Bioactive molecules are practical tools for regulating cellular processes and have been applied to control cellular differentiation, dedifferentiation, and reprogramming. In this review, we focus on recent progress in the use of bioactive molecules in skin regenerative medicine, by which desired cell types can be generated in vitro for cell therapy and conventional therapeutics can be developed to repair and regenerate skin in vivo through activation of the endogenous repairing potential. We further prospect that the bioactive molecule-base method might be one of the promising strategies to achieve in situ skin regeneration in the future. |
| format | Article |
| id | doaj-art-b38815d59f374dc89ea898c2563caa14 |
| institution | Kabale University |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-b38815d59f374dc89ea898c2563caa142025-02-03T05:59:42ZengWileyStem Cells International1687-966X1687-96782019-01-01201910.1155/2019/67898236789823Bioactive Molecules for Skin Repair and Regeneration: Progress and PerspectivesDeyun Chen0Qian Hou1Lingzhi Zhong2Yali Zhao3Meirong Li4Xiaobing Fu5Wound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, ChinaWound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, ChinaWound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, ChinaTrauma Treatment Center, Central Laboratory, Chinese PLA General Hospital, Hainan Branch, 9 Haitang Bay, Sanya 572014, ChinaWound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, ChinaWound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing 100853, ChinaSkin regeneration is a vexing problem in the field of regenerative medicine. A bioactive molecule-based strategy has been frequently used in skin wound healing in recent years. Bioactive molecules are practical tools for regulating cellular processes and have been applied to control cellular differentiation, dedifferentiation, and reprogramming. In this review, we focus on recent progress in the use of bioactive molecules in skin regenerative medicine, by which desired cell types can be generated in vitro for cell therapy and conventional therapeutics can be developed to repair and regenerate skin in vivo through activation of the endogenous repairing potential. We further prospect that the bioactive molecule-base method might be one of the promising strategies to achieve in situ skin regeneration in the future.http://dx.doi.org/10.1155/2019/6789823 |
| spellingShingle | Deyun Chen Qian Hou Lingzhi Zhong Yali Zhao Meirong Li Xiaobing Fu Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives Stem Cells International |
| title | Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives |
| title_full | Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives |
| title_fullStr | Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives |
| title_full_unstemmed | Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives |
| title_short | Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives |
| title_sort | bioactive molecules for skin repair and regeneration progress and perspectives |
| url | http://dx.doi.org/10.1155/2019/6789823 |
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