Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?

Oral sodium phosphate (NaP) solution has been withdrawn from the market in the United States but remains available for over-the-counter purchase for bowel preparation for colonoscopy in Canada. The present review summarizes recent data regarding the renal toxicity of oral NaP as well as its efficacy...

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Main Authors: Douglas K Rex, Stephen J Vanner
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2009/417296
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author Douglas K Rex
Stephen J Vanner
author_facet Douglas K Rex
Stephen J Vanner
author_sort Douglas K Rex
collection DOAJ
description Oral sodium phosphate (NaP) solution has been withdrawn from the market in the United States but remains available for over-the-counter purchase for bowel preparation for colonoscopy in Canada. The present review summarizes recent data regarding the renal toxicity of oral NaP as well as its efficacy and tolerability relative to other preparations. Given the availability of effective alternatives to NaP solution, its use for colonoscopy preparation in Canada should be limited. Candidate patients for oral NaP solution should be assessed for eligibility and preparation instructions should adhere to the current recommendations for maximizing the safety of oral NaP.
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spelling doaj-art-b384456cf6f34e11ad36c357c3828d842025-02-03T06:06:01ZengWileyCanadian Journal of Gastroenterology0835-79002009-01-0123321021410.1155/2009/417296Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?Douglas K Rex0Stephen J Vanner1Indiana University Medical Center, Indianopolis, Indiana, USAGastrointestinal Diseases Research Unit, Kingston General Hospital, Queen’s University, Kingston, Ontario, CanadaOral sodium phosphate (NaP) solution has been withdrawn from the market in the United States but remains available for over-the-counter purchase for bowel preparation for colonoscopy in Canada. The present review summarizes recent data regarding the renal toxicity of oral NaP as well as its efficacy and tolerability relative to other preparations. Given the availability of effective alternatives to NaP solution, its use for colonoscopy preparation in Canada should be limited. Candidate patients for oral NaP solution should be assessed for eligibility and preparation instructions should adhere to the current recommendations for maximizing the safety of oral NaP.http://dx.doi.org/10.1155/2009/417296
spellingShingle Douglas K Rex
Stephen J Vanner
Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
Canadian Journal of Gastroenterology
title Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
title_full Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
title_fullStr Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
title_full_unstemmed Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
title_short Colon Cleansing before Colonoscopy: Does Oral Sodium Phosphate Solution Still Make Sense?
title_sort colon cleansing before colonoscopy does oral sodium phosphate solution still make sense
url http://dx.doi.org/10.1155/2009/417296
work_keys_str_mv AT douglaskrex coloncleansingbeforecolonoscopydoesoralsodiumphosphatesolutionstillmakesense
AT stephenjvanner coloncleansingbeforecolonoscopydoesoralsodiumphosphatesolutionstillmakesense