New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma
In the management of patients with prostate cancer, the development of new radiographic findings can mimic progression of the disease, thereby triggering changes in treatment. Typically, clinicians evaluate additional parameters, such as symptoms and prostate specific antigen (PSA) levels, for furth...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/358572 |
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| author | Ellen A. Szwed Sarunas Sliesoraitis Thu-Cuc Nguyen Minh-Nguyet Nguyen Jan S. Moreb Robert A. Zlotecki Paul L. Crispen Nam H. Dang Long H. Dang |
| author_facet | Ellen A. Szwed Sarunas Sliesoraitis Thu-Cuc Nguyen Minh-Nguyet Nguyen Jan S. Moreb Robert A. Zlotecki Paul L. Crispen Nam H. Dang Long H. Dang |
| author_sort | Ellen A. Szwed |
| collection | DOAJ |
| description | In the management of patients with prostate cancer, the development of new radiographic findings can mimic progression of the disease, thereby triggering changes in treatment. Typically, clinicians evaluate additional parameters, such as symptoms and prostate specific antigen (PSA) levels, for further evidence of disease progression. In the absence of additional findings, for example, elevated PSA, the possibility of an additional malignancy should be considered and evaluated. We present three cases of patients undergoing treatment for prostate adenocarcinoma and discovered on imaging to have findings suggestive of disease progression, but ultimately found to be a new primary malignancy. Our cases suggest that, in patients with prostate cancer, the appearance of new lymphadenopathy or bone lesions cannot be assumed to solely represent progression of the prostate cancer and warrant further investigation, especially in the presence of stable PSA levels. |
| format | Article |
| id | doaj-art-b38060c1bea744c3bf3227f9e3ab48bd |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-b38060c1bea744c3bf3227f9e3ab48bd2025-02-03T06:11:41ZengWileyCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/358572358572New Primary Malignancy Masquerading as Metastatic Prostate AdenocarcinomaEllen A. Szwed0Sarunas Sliesoraitis1Thu-Cuc Nguyen2Minh-Nguyet Nguyen3Jan S. Moreb4Robert A. Zlotecki5Paul L. Crispen6Nam H. Dang7Long H. Dang8Division of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADepartment of Radiation Oncology, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADepartment of Urology, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USADivision of Hematology and Oncology, Department of Internal Medicine, University of Florida Shands Cancer Center, 1600 SW Archer Road, Gainesville, FL 32610, USAIn the management of patients with prostate cancer, the development of new radiographic findings can mimic progression of the disease, thereby triggering changes in treatment. Typically, clinicians evaluate additional parameters, such as symptoms and prostate specific antigen (PSA) levels, for further evidence of disease progression. In the absence of additional findings, for example, elevated PSA, the possibility of an additional malignancy should be considered and evaluated. We present three cases of patients undergoing treatment for prostate adenocarcinoma and discovered on imaging to have findings suggestive of disease progression, but ultimately found to be a new primary malignancy. Our cases suggest that, in patients with prostate cancer, the appearance of new lymphadenopathy or bone lesions cannot be assumed to solely represent progression of the prostate cancer and warrant further investigation, especially in the presence of stable PSA levels.http://dx.doi.org/10.1155/2015/358572 |
| spellingShingle | Ellen A. Szwed Sarunas Sliesoraitis Thu-Cuc Nguyen Minh-Nguyet Nguyen Jan S. Moreb Robert A. Zlotecki Paul L. Crispen Nam H. Dang Long H. Dang New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma Case Reports in Oncological Medicine |
| title | New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma |
| title_full | New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma |
| title_fullStr | New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma |
| title_full_unstemmed | New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma |
| title_short | New Primary Malignancy Masquerading as Metastatic Prostate Adenocarcinoma |
| title_sort | new primary malignancy masquerading as metastatic prostate adenocarcinoma |
| url | http://dx.doi.org/10.1155/2015/358572 |
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