Cytokines and Other Mediators in Alopecia Areata
Alopecia areata, a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin, has been extensively studied as far as the role of several cytokines is concerned. So far, IFN-𝛾, interleukins, TNF-𝛼, are cytokines that are well known to play a major role in...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2010/928030 |
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| _version_ | 1832556974511751168 |
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| author | Stamatis Gregoriou Dafni Papafragkaki George Kontochristopoulos Eustathios Rallis Dimitrios Kalogeromitros Dimitris Rigopoulos |
| author_facet | Stamatis Gregoriou Dafni Papafragkaki George Kontochristopoulos Eustathios Rallis Dimitrios Kalogeromitros Dimitris Rigopoulos |
| author_sort | Stamatis Gregoriou |
| collection | DOAJ |
| description | Alopecia areata, a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin, has been extensively studied as far as the role of several cytokines is concerned. So far, IFN-𝛾, interleukins, TNF-𝛼, are cytokines that are well known to play a major role in the pathogenesis of the disease, while several studies have shown that many more pathways exist. Among them, MIG, IP-10, BAFF, HLA antigens, MIG, as well as stress hormones are implicated in disease onset and activity. Within the scope of this paper, the authors attempt to shed light upon the complexity of alopecia areata underlying mechanisms and indicate pathways that may suggest future treatments. |
| format | Article |
| id | doaj-art-b362ac96085b40979c3b7e8be4ec5fd0 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-b362ac96085b40979c3b7e8be4ec5fd02025-02-03T05:43:56ZengWileyMediators of Inflammation0962-93511466-18612010-01-01201010.1155/2010/928030928030Cytokines and Other Mediators in Alopecia AreataStamatis Gregoriou0Dafni Papafragkaki1George Kontochristopoulos2Eustathios Rallis3Dimitrios Kalogeromitros4Dimitris Rigopoulos5Andreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAndreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAndreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAndreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAndreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAndreas Sygros Hospital, University of Athens Medical School, 5 Ionos Dragoumi Street, 16121 Athens, GreeceAlopecia areata, a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin, has been extensively studied as far as the role of several cytokines is concerned. So far, IFN-𝛾, interleukins, TNF-𝛼, are cytokines that are well known to play a major role in the pathogenesis of the disease, while several studies have shown that many more pathways exist. Among them, MIG, IP-10, BAFF, HLA antigens, MIG, as well as stress hormones are implicated in disease onset and activity. Within the scope of this paper, the authors attempt to shed light upon the complexity of alopecia areata underlying mechanisms and indicate pathways that may suggest future treatments.http://dx.doi.org/10.1155/2010/928030 |
| spellingShingle | Stamatis Gregoriou Dafni Papafragkaki George Kontochristopoulos Eustathios Rallis Dimitrios Kalogeromitros Dimitris Rigopoulos Cytokines and Other Mediators in Alopecia Areata Mediators of Inflammation |
| title | Cytokines and Other Mediators in Alopecia Areata |
| title_full | Cytokines and Other Mediators in Alopecia Areata |
| title_fullStr | Cytokines and Other Mediators in Alopecia Areata |
| title_full_unstemmed | Cytokines and Other Mediators in Alopecia Areata |
| title_short | Cytokines and Other Mediators in Alopecia Areata |
| title_sort | cytokines and other mediators in alopecia areata |
| url | http://dx.doi.org/10.1155/2010/928030 |
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